Psychotropics and Related Topics From
Sixteen Years of Peer-Review Articles

NOTE FOR READERS: While most pharmacologic agents are called out by name, some articles may be overviews of entire classes of agents. For example, under sections such as ANTIDEPRESSANTS (not specified), the reader would find the following article: Rational Antidepressant Selection: Applying Evidence-Based Medicine to Complex Real-World Patients.

Likewise, certain pharmacologic advances can be rationalized only in the context of the disease itself. Among drug categories, you will find ‘non specified’ sections on Epidemiology, Bipolar, and Sleep Disturbances, to name just a few. Rather than omit entire categories of research because they did not correspond to a strict listing of drug names, we chose to deviate in certain instances for the sake of completeness. We hope this does not contribute to any confusion.

All articles prefaced with the    logo are indexed on PubMed.com under Psychopharmacol Bull.
— Sincerely, The Editors

DISCLAIMER: Although every effort has been made to ensure that drug information is presented accurately in all Medworks’ publications, the ultimate responsibility rests with the prescribing physician. Neither the publisher, nor the authors can be held responsible for errors or for any consequences arising from the use of information contained herein. Readers are strongly urged to consult additional relevant primary literature. No claims or endorsements are made for any drug or compound currently under clinical investigation.

ADHD (Not Specified)

 – Persisting Psychosocial Impairments in Adults Being Treated with Medication for Attention Deficit/Hyperactivity Disorder

 – Unmet Medication Coverage Needs among Adults with Attention Deficit/Hyperactivity Disorder (ADHD)

Agomelatine

 – Agomelatine for Depression in Schizophrenia: A Case-Series

Alprazolam

 – The Speed of Onset of Action of Alprazolam-XR Compared to Alprazolam-CT in Panic Disorder

Alzheimer’s

 – Progressive Non-familial Adult onset Cerebellar Degeneration: An Unusual Occurrence with Hashimoto’s Thyroiditis

Alternative Medicine

 – Determinants of Complementary and Alternative Medicine Use by Patients with Bipolar Disorder 

Ambulatory Pschiatry (Not Specified)

 – Collaborative Care in Ambulatory Psychiatry: Content Analysis of Consultations to a Psychiatric Pharmacist

Amisulpride

 – Amisulpride for Clozapine Induced Sialorrhea

Amitriptyline

 – Citalopram Versus Amitriptyline in Elderly Depressed Patients with or without Mild Cognitive Dysfunction: A Danish Multicentre Trial in General Practice

Anticonvulsants (not specified)

 – Evidence-Based Mental Health Use of Anticonvulsants During Pregnancy

 – Pharmacokinetics of Mood Stabilizers and New Anticonvulsants 

Innovative Treatment Strategies With Anticonvulsants: A Focus On Bipolar Disorder 

Antidepressants (not specified)

 – Rational Antidepressant Selection: Applying Evidence-Based Medicine to Complex Real-World Patients

 – Comparing The Methods Used To Compare Antidepressants 

 – A Survey of Prescribing Preferences in the Treatment of Refractory Depression: Recent Trends 

Great Expectations In Stereochemistry: Focus On Antidepressants 

A Discussion On The Methodologies Used To Evaluate Antidepressants 

 –Impact Of A Student Pharmacist Driven Medication Reconciliation And Antidepressant Treatment History Project At A Depression Clinic: A Pilot Study

Antipsychotics (not specified)

 – Three-Year Naturalistic Study On Early Use Of Long-Acting Injectable Antipsychotics In First Episode Psychosis

 – Do Long-Acting Injectable Antipsychotics Prevent or Delay Hospital Readmission?

 – Lack of Efficacy of Antipsychotics on Premenstrual Psychosis: A Case Report

 – Antipsychotic Induced Symptomatic Hyperprolactinemia: Are Dopamine Agonists Safe? 

 – Metabolic Syndrome with Different Antipsychotics: A Multicentre Cross-Sectional Study 

 – The Revised Dopamine Hypothesis of Schizophrenia: Evidence from Pharmacological MRI Studies with Atypical Antipsychotic Medication 

 – Antipsychotic Medications and Sudden Cardiac Death 

 – Antipsychotic-Induced Hyperprolactinemia and Sexual Dysfunction 

 – Sexual Side Effects Associated With Conventional and Atypical Antipsychotics 

 – Therapeutic Drug Monitoring of Antipsychotics 

 –Combined Antipsychotics And Electroconvulsive Therapy In An Acutely Psychotic Patient With Treatment-Resistant Schizophrenia

 –Sex Differences In Antipsychotic Related Metabolic Functioning In Schizophrenia Spectrum Disorders

Arpiprazole Lauroxil

 – A Phase-1 Study Comparing Pharmacokinetic And Safety Profiles Of Three Different Dose Intervals Of Aripiprazole Lauroxil

 – Metabolic And Endocrine Profiles During 1-Year Treatment Of Outpatients With Schizophrenia With Aripiprazole Lauroxil

Atomoxetine

 – Atomoxetine Induced Hypothermia: A Case Report 

Aripiprazole

 – Criteria for Defining Symptomatic and Sustained Remission in Bipolar I Disorder: a Post-Hoc Analysis of a 26-Week Aripiprazole Study (Study CN138-010) 

 – An Open-Label Assessment of Aripiprazole in the Treatment of PTSD 

 – Efficacy of High-Dose Aripiprazole for Treatment-Resistant Schizoaffective Disorder: A Case Report

 – Prospective Study to Evaluate the Efficacy of Aripiprazole as a Monotherapy in Patients with Severe Chronic Posttraumatic Stress Disorder: An Open Trial 

 -Aripiprazole-Induced Asymptomatic Hypertension: A Case Report

Asenapine

 – An Open Label Pilot Study Of Adjunctive Asenapine For The Treatment Of Posttraumatic Stress Disorder

 – Asenapine in the Treatment of Negative Symptoms of Schizophrenia: Clinical Trial Design and Rationale

Atypical Antipsychotics (not specified)

 – The Utilization of Atypical Antipsychotics in the Pain Medicine Physician’s Armamentarium

 – Atypical Antipsychotic Drugs and Diabetes Mellitus in the US Food and Drug Administration Adverse Event Database: A Systematic Bayesian Signal Detection Analysis 

 – Off-Label Second Generation Antipsychotics for Impulse Regulation Disorders: A Review 

 – Predicting Antipsychotic Use in Children 

 – Drug–Drug Interactions Associated with Second-Generation Antipsychotics: Considerations for Clinicians and Patients

 – Atypical Antipsychotics and Pituitary Neoplasms in the WHO Database 

 – Mood Stabilizers and Atypical Antipsychotics: Bimodal Treatments for Bipolar Disorder 

 – Drug Development for Anxiety Disorders: New Roles for Atypical Antipsychotics 

 – Advancing the Treatment of Anxiety Disorders: New Findings and Novel Uses for Atypical Antipsychotics

 – Disturbed Glucose Metabolism Among Patients Taking Olanzapine and Typical Antipsychotics 

 – Sexual Side Effects Associated With Conventional and Atypical Antipsychotics

Human And Economic Costs Of Schizophrenia: A Case Study Of The Impact Of Newer Antipsychotics 

Autism Spectrum Disorder(s) (not specified)

 – The Use of Complementery Alternative Medicine in Children and Adolescents with Autism Spectrum Disorder

 – Treatment Of Autism Spectrum Disorder In Children And Adolescents

 – Does Risperidone Improve Hyperacusia in Children with Autism? 

Benzodiazepines (not specified)

 – A Major Change of Prescribing Pattern in Absence of Adequate Evidence: Benzodiazepines Versus Newer Antidepressants in Anxiety Disorders

 – Pharmacokinetically Induced Benzodiazepine Withdrawal 

Bipolar Disorders (not specified)

 – Rating Scales And Safety Measurements In Bipolar Disorder And Schizophrenia – A Reference Guide

 – Rapid Cycling Bipolar Disorder and a Recent Substance Use Disorder: A 12-week, Double-Blind, Placebo-Controlled Pilot Study

 – Why Do Persons with Bipolar Disorder Stop Their Medication?

 – Bipolar-I Patient Characteristics Associated with Differences in Antimanic Medication Prescribing

 – Frequency of Stimulant Treatment and of Stimulant-Associated Mania/Hypomania in Bipolar Disorder Patients

 – Correlates of Functioning in Bipolar Disorder 

 – Bipolar-I Depression Outpatient Treatment Quality and Costs in Usual Care Practice 

 – Patterns of Pharmacotherapy and Treatment Response in Elderly Adults with Bipolar Disorder

 – Concordance with Treatment Guidelines for Bipolar Disorder: Data from the Systematic Treatment Enhancement Program for Bipolar Disorder 

 – Mood Stabilizers and Atypical Antipsychotics: Bimodal Treatments for Bipolar Disorder 

 – New Approaches to Modeling Bipolar Disorder 

 – Management of Bipolar Disorder in Children and Adolescents 

 – An Evidence-Based Review of Psychosocial Treatments for Bipolar Disorder 

 – Genetics Of Bipolar Disorder 

Bipolar Affective Disorder: Does Psychosocial Treatment Add To The Efficacy Of Drug Therapy?

The Neurobiology Of Bipolar Disorder

Expert Consensus Guidelines For The Medication Treatment Of Bipolar Disorder: A New Treatment Tool

A Test For Bipolar Disorder: The Mood Disorder Questionnaire 

STEP- BD—A Design For Evaluating Effectiveness Of Treatment For Bipolar Disorder

The TEN Interview: Kay Redfield Jamison, PhD

Attention-Deficit/Hyperactivity Disorder And Pediatric-Onset Bipolar Disorder 

Bupropion

 – Monoarthritis Induced by Bupropion Hydrochloride

 – Bupropion Sustained Release for Panic Disorder 

 – Effect of Bupropion SR on Specific Symptom Clusters of Depression: Analysis of the 31-Item Hamilton Rating Scale for Depression 

Caffeine

 – A Primer on Caffeine Pharmacology and Its Drug Interactions in Clinical Psychopharmacology

Cannabis

 – Recent-Onset Schizophrenia and Adolescent Cannabis Use: MRI Evidence for Structural Hyperconnectivity?

 – Cessation of Cannabis Use by Patients with Recent-Onset Schizophrenia and Related Disorders

Citalopram

 – Citalopram Versus Amitriptyline in Elderly Depressed Patients with or without Mild Cognitive Dysfunction: A Danish Multicentre Trial in General Practice

 – Can Physiologic Assessment and Side Effects Tease Out Differences in PTSD Trials? A Double-Blind Comparison of Citalopram, Sertraline, and Placebo

 – Overview of the Safety of Citalopram

 – Citalopram for the Treatment of Adolescent Anxiety Disorders: A Pilot Study

Efficacy Comparison Of Escitalopram And Citalopram In The Treatment Of Major Depressive Disorder: Pooled Analysis Of Placebo-Controlled Trials

Clinical Trials (standards & strategies)

 – A Pilot Evaluating Clinical Pharmacy Services in an Ambulatory Psychiatry Setting

 – Rater Training for a Multi-Site, International Clinical Trial: What Mood Symptoms may be most Difficult to Rate?

 – Which Rating Scales are Regarded as ‘The Standard’ in Clinical Trials for Schizophrenia? A Critical Review

 – Statistical Strategies for Randomized Controlled Clinical Trials to Detect Differential Onset of Action

 – Assessment of Anxiety in Clinical Trials with Depressed Patients Using the Hamilton Depression Rating Scale

 – The Sex Effects Scale: Pilot Validation in a Healthy Population

 – Exercise for Depression: Efficacy, Safety and Clinical Trial Implications

 – Psychometric Evaluation of a Patient-Rated Troubling Symptom Scale for Generalized Anxiety Disorder Clinical Trials

 – Addressing Methodological Issues in Studying Antidepressant Onset Efficacy Using Prespecified Sensitivity Analyses

 – Early Symptom Change Prediction of Remission in Depression Treatment

 – Placebo Response in Depression: A Perspective for Clinical Practice

 – Psychometric Evaluation of a Patient-Rated Troubling Symptom Scale for Generalized Anxiety Disorder Clinical Trials

 – Developing and Testing Adaptive Treatment Strategies Using Substance-Induced Psychosis as an Example.

 – Simple Options for Improving Signal Detection in Antidepressant Clinical Trials

 – Reliability and Validity of the Yale-Brown Obsessive-Compulsive Scale in Schizophrenia Patients

 – What Is a Significant Response in Drug Studies of Attention- Deficit/Hyperactivity Disorder: Statistical Significance Is Necessary, But Is It Sufficient?

 – An Intent-to-Treat Method for Enhancing Analysis of Clinical Trials with Rescue Medication: A Mixed-Model Approach

 – The Duke Somatic Treatment Algorithm for Geriatric Depression (STAGED) Approach

 – Informant-Rated Cognitive Symptoms in Normal Aging, Mild Cognitive Impairment, and Dementia

 – Clinical Trials in Alzheimer’s Disease

Placebo-Controlled Trials In Psychiatric Research: An Ethical Perspective

Ethics And Economics In Placebo-Controlled Trials Of New Drugs For Mood Disorders

Reconsidering Outcomes In Alzheimer Disease Clinical Trials

Clozapine

 – A Case of Hyper Sexuality Probably Associated with Clozapine

 – Differences in Efficacy on Substance Abuse between Risperidone and Clozapine Supports the Importance of Differential Modulation of Dopaminergic Neurotransmission

 – Amisulpride for Clozapine Induced Sialorrhea

 – Clinical Predictors of Response to Clozapine in Patients with Treatment Resistant Schizophrenia

 – Suicidal Obsessions as Dose Dependent Side-Effect of Clozapine

 – Complete Resolution of Clozapine-Induced Sialorrhea with Low Dose Trihexyphenidyl

 – Amisulpride for Clozapine Induced Sialorrhea

 – Factors Associated with Response to Clozapine in Schizophrenia: A Review

 – Switching antipsychotics, pharmacokinetics, pharmacodynamics, crossover, abrupt switch, clozapine, olanzapine, ziprasidone

Cocaine

 – Cocaine is a Major Risk Factor for Antipsychotic Induced Akathisia, Parkinsonism and Dyskinesia.

 – Acute Cortisol Administration Triggers Craving in Individuals with Cocaine Dependence

Comorbidity

 – A Pilot Evaluating Clinical Pharmacy Services in an Ambulatory Psychiatry Setting

 – Major Depression Comorbid with Medical Conditions: Analysis of Quality of Life Functioning, and Depressive Symptom Severity

Cortisol

 – Acute Cortisol Administration Triggers Craving in Individuals with Cocaine Dependence

Cyclobenzaprine

 – Induction of Psychosis by Cyclobenzaprine

DDTC (a Metabolite of Disulfiram)

 – DDTC, a Metabolite of Disulfiram, Reduces the Stimulating Effect on Ethanol’s Locomotor Activity in Mice 

Dementia

 – Progressive Non-familial Adult onset Cerebellar Degeneration: An Unusual Occurrence with Hashimoto’s Thyroiditis

Depression

 – Major Depression Comorbid with Medical Conditions: Analysis of Quality of Life Functioning, and Depressive Symptom Severity

Dextromethorphan

 Dextromethorphan in Cough Syrup: The Poor Man’s Psychosis

Desvenlafaxine

 – Analysis Of Symptoms In Patients With Major Depressive Disorder Treated With Desvenlafaxine Or Placebo

 – Desvenlafaxine and Venlafaxine Exert Minimal In Vitro Inhibition of Human Cytochrome P450 and P-Glycoprotein Activities

Dextromethorphan

 – Treatment Resistant Depression With Loss Of Antidepressant Response: Rapid—Acting Antidepressant Action Of Dextromethorphan, A Possible Treatment Bridging Molecule. 

Donepezil

 – Donepezil for Cognitive Decline Following Coronary Artery Bypass Surgery: A Pilot Randomized Controlled Trial

Drug Interactions (not specified)

 – 2018 Update: Dosing and Monitoring: Children and Adolescents

 – 2018 Update: The Black Book of Psychotropic Dosing and Monitoring

 – Clinical Significance of Drug Binding, Protein Binding, and Binding Displacement Drug Interactions

 – Psychoactive Drug Interactions With Pharmacotherapy for Diabetes 

 – Emerging Significance of P-glycoprotein in Understanding Drug Disposition and Drug Interactions in Psychopharmacology 

 – Emerging Role of Drug Interaction Studies in Drug Development:The Good, the Bad, and the Unknown

 – Charleston Antidepressant Drug Interactions Surveillance Program (CADISP) 

 – The Emerging Recognition of Herb-Drug Interactions With a Focus on St. John’s Wort (Hypericum Perforatum)

 – An Explanation of the Second-Dose Effect in Pharmacokinetics and Its Meaning for Clinical Psychopharmacology 

Dopamine D4 Receptors: Neuropsychiatric Implications 

Psychotropic Drug Interactions : A Doctor’s Guide

Duloxetine

 – Duloxetine in Military Posttraumatic Stress Disorder

 – Switching to Duloxetine Remits Ziprasidone – Associated Urinary Incontinence and Improves Neuropsychiatric Behavior in Dementia: Possible Relationship of Incontinence to 5HT2 Receptor Blockade.

 – Duloxetine for the Treatment of Major Depressive Disorder 

ECT

 – Treatment of Mania in Dementia With Electroconvulsive Therapy 

 –Combined Antipsychotics And Electroconvulsive Therapy In An Acutely Psychotic Patient With Treatment-Resistant Schizophrenia

Epidemiology (not specified)

 – Epidemiology Of Adolescent Depression

 – Pharmacologic And Psychotherapeutic Treatments For Adolescent Depression 

 – Obesity Cost-Of-Illness Studies: An International Perspective 

 – Drug Use And Dependence Outside Medical Settings: Recent Epidemiological Evidence 

 – The Epidemiology of Anxiety Disorders 

 – Genetic Epidemiology of Drug Use Disorders

 – Healthcare Costs For Children With Attention-Deficit/Hyperactivity Disorder 

 – Expert Consensus Guidelines For The Treatment Of Depression In Women: A New Treatment Tool 

 – The NIMH Women’s Mental Health Program: Establishing the Public Health Context For Women’s Mental Health

 – Diagnosis, Epidemiology, And Clinical Course Of Geriatric Depression 

 – Determinants Of Medical Costs Following A Diagnosis of Depression

Escitalopram

 – Escitalopram Induced SIADH in an Elderly Female: A Case Study

 – Hypomania Induced by Escitalopram: 2 Case Reports.

 – Sexual Pain Among Malaysian Women Receiving Antidepressant: A Comparison Between Escitalopram And Fluoxetine

Efficacy Comparison Of Escitalopram And Citalopram In The Treatment Of Major Depressive Disorder: Pooled Analysis Of Placebo-Controlled Trials 

Escitalopram: A Second-Generation SSRI 

Paliperidone

 – Effects Of Discontinuation Of Paliperidone Long-Acting Injectable After Switching From Risperidone Long-Acting Injectable Switching

 – Efficacy and Safety of Paliperidone Extended Release 1.5 mg/day—A Double-blind, Placebo- and Active-Controlled, Study in the Treatment of Patients with Schizophrenia

 – Paliperidone Palmitate Treatment In Outpatient Care Setting: A Naturalistic Study

 – Long-Acting Injectable Paliperidone Palmitate: A Review Of Efficacy And Safety

Panic Disorder (not specified)

 – Management of Treatment-Refractory Panic Disorder

Panic Disorder During Pregnancy

Paroxetine

 – Efficacy and Tolerability of Two Different Kinds of Titration of Paroxetine Hydrocloride Solution: an Observational Study

 – Paroxetine—The Antidepressant From Hell? Probably Not, But Caution Required

 – Neuropsychological Functioning in Patients with Posttraumatic Stress Disorder Following Short-Term Paroxetine Treatment

 – Brief Report: Paroxetine in Younger and Adult Individuals at High Risk for Suicide

 – A Randomized Controlled Trial of Paroxetine for Noncardiac Chest Pain

 – Neuropharmacology of Paroxetine

 – In Vivo Neuroimaging Correlates of the Efficacy of Paroxetine in the Treatment of Mood and Anxiety Disorders

 – Pharmacokinetics, Drug Interactions, and Tolerability of Paroxetine and Paroxetine CR

 – Paroxetine Treatment of Major Depressive Disorder

 – Treatment of Panic Disorder: Focus on Paroxetine

 – Paroxetine Treatment of Generalized Anxiety Disorder

 – Treatment of Posttraumatic Stress Disorder: The Impact of Paroxetine

 – Obsessive-Compulsive Disorder: Implications of the Efficacy of an SSRI, Paroxetine

 – Advances in Recognition and Treatment of Social Anxiety Disorder: A 10-Year Retrospective

 – Paroxetine Use in Medically Ill Patients

 – Paroxetine Treatment of Depression in Late Life

 – Paroxetine Treatment of Mood Disorders in Women: Premenstrual Dysphoric Disorder and Hot Flashes

 – Clinical Management of Perinatal Depression: Focus on Paroxetine

 – Paroxetine Treatment of Mood and Anxiety Disorders in Children and Adolescents

 – Efficacy and Tolerability of Controlled-Release Paroxetine

Placebo (not specified)

 – Suicide Risk Analysis Among Patients Assigned to Psychotropics and Placebo

 – Can Physiologic Assessment and Side Effects Tease Out Differences in PTSD Trials? A Double-Blind Comparison of Citalopram, Sertraline, and Placebo

PMDD (Premenstrual Dysphoric Disorder)

 – An Interesting Presentation About Cyclical Menstrual Psychosis with an Updated Review of Literature

Prednisone

 – Drug Dependence Involving Prednisone:Two Cases and a Review of the Literature

Pseudoephedrine

 – Successful Management of Psychotropics Induced Stuttering Priapism with Pseudoephedrine in a Patient with Schizophrenia

Psychopharmacology (not specified)

 – Evidence-Based Decision-Making in Psychopharmacology

 – An Evidence-Based Medicine Approach to Combined Treatment for ADHD in Children and Adolescents

 – The Psychopharmacology of Fibromyalgia: A Drug Development Perspective

 – Special Issues in the Psychopharmacological Management of Hispanic Americans

Pharmacologic Management Of Attention-Deficit/Hyperactivity Disorder

Psychotherapy (not specified)

 – REVAMP – Research Evaluating the Value of Augmenting Medication with Psychotherapy: Rationale and Design

 – Continuation Treatment of Chronic Depression: A Comparison of Nefazodone, Cognitive Behavioral Analysis System of Psychotherapy, and Their Combination

Efficacy And Cost-Effectiveness Of Group Psychotherapy For Patients With Cancer

Movement Toward Evidence-Based Psychotherapies

Psychotropics – Dosing – New

 – NEWLY UPDATED – The Black Book of Psychotropic Dosing and Monitoring – 2018

Schizophrenia (not specified)

 – Successful Management of Psychotropics Induced Stuttering Priapism with Pseudoephedrine in a Patient with Schizophrenia

 – Rating Scales And Safety Measurements In Bipolar Disorder And Schizophrenia – A Reference Guide

 – Signal Detection and Placebo Response in Schizophrenia: Parallels with Depression 

 – Paroxysmal Perceptual Alteration: Drug-Induced Phenomenon or Schizophrenic Psychopathology? 

 – Financial Incentives to Improve Adherence to Medication in Five Patients with Schizophrenia in The Netherlands

 – Treatment Target in Schizophrenia: A Critical Review and a Clinical Suggestion 

 – The Revised Dopamine Hypothesis of Schizophrenia: Evidence from Pharmacological MRI Studies with Atypical Antipsychotic Medication

 – Do Antipsychotic Drugs Influence Suicidal Behavior in Schizophrenia?

 – Neurodevelopmental Models of Schizophrenia: Pathophysiologic Synthesis and Directions for Intervention Research 

Pharmacologic Treatment Of Schizophrenia

Gender And Schizophrenia 

Genetics Of Schizophrenia: Recent Advances 

Neuropsychiatric Update: Neuroimaging Schizophrenia

Ethical Issues In Schizophrenia: Considerations For Treatment And Research

 –Sex Differences In Antipsychotic Related Metabolic Functioning In Schizophrenia Spectrum Disorders

Selegiline

 – Commentary on the Treatment Effects of Selegiline Transdermal System on Symptoms of Major Depressive Disorder: A Meta-Analysis of Short-Term, Placebo-Controlled, Efficacy Trials 

Sertraline

 – Can Physiologic Assessment and Side Effects Tease Out Differences in PTSD Trials? A Double-Blind Comparison of Citalopram, Sertraline, and Placebo

Sleep Disorders (not specified)

Sleep Disorders Centers—Function, Structure, And Economics

Shiftwork, Circadian Disruption, And Consequences 

Recent Advances In The Understanding And Treatment Of Narcolepsy

Comorbidity Of Insomnia With Medical And Psychiatric Disorders

SSRIs/SNRIs (not specified)

 – Are SNRIs More Effective than SSRIs? A Review of the Current State of the Controversy 

 – A Pilot Study of the Pharmacodynamic Impact of SSRI Drug Selection and Beta-1 Receptor Genotype (ADRB1) on Cardiac Vital Signs in Depressed Patients: A Novel Pharmacogenetic Approach 

 – A Model to Explain the Therapeutic Effects of Serotonin Reuptake Inhibitors: The Role of 5-HT2 Receptors

 – Can Serotonin and Fluoxetine Levels in Plasma and Platelets Predict Clinical Response in Depression? 

 – Serotonin Reuptake Inhibitors: Pharmacoeconomic Cost-Effective Modeling In A University Psychiatric Outpatient Clinic 

St. John’s Wort

 – The Emerging Recognition of Herb-Drug Interactions With a Focus on St. John’s Wort (Hypericum Perforatum)

Stimulants (not specified)

 – Frequency of Stimulant Treatment and of Stimulant-Associated Mania/Hypomania in Bipolar Disorder Patients

 – Photophobia and Methylphenidate 

 – Management of Treatment Refractory Attention-Deficit/Hyperactivity Disorder in Children and Adolescents 

 – Treatment Of Children With Attention-Deficit/Hyperactivity Disorder: Results Of A Randomized, Multicenter, Double-Blind, Crossover Study Of Extended-Release Dexmethylphenidate And DL – Methylphenidate And Placebo In A Laboratory Classroom Setting

Suicide Prevention (not specified)

Editor’s Letter: Suicide

The Economic Burden of Suicide In The United States 

Acute Vs Chronic Risk Factors For Suicide— Treatment Implications 

Valbenazine

 – Efficacy Of Valbenazine In Treating Subjects With Tardive Dyskinesia And Mood Disorder

 – Efficacy Of Valbenazine In Treating Subjects With Tardive Dyskinesia And Schizophrenia Or Schizoaffective Disorder

 – Long-Term Safety And Tolerability Of Valbenazine In Subjects With Tardive Dyskinesia And A Diagnosis Of Schizophrenia Or Mood Disorder

 – Single Dose And Repeat Once-Daily Dose Safety, Tolerability And Pharmacokinetics Of Valbenazine In Healthy Male Subjects

Valproic Acid

 – Valproic Acid And Hepatic Steatosis: A Possible Link? About A Case Report
Genomics. 

 – Valproate Use in Neuropsychiatric Disorders in the Elderly 

 – Divalproex in the Treatment of Migraine 

 – The Use of Divalproex in the Treatment of Addictive Disorders 

 – Schizophrenia and Valproate 

 – Divalproex in the Treatment of Bipolar Disorder 

 – The Efficacy of Divalproex for Partial Epilepsies

 – Divalproex and Epilepsy 

 – Pharmacokinetics, Drug Interactions, and Tolerability of Valproate 

 – Pharmacology of Valproate 

 – The History of Valproate in Clinical Neuroscience 

 – Predictors of Non-Stabilization during the Combination Therapy of Lithium and Divalproex in Rapid Cycling Bipolar Disorder: A Post-hoc Analysis of Two Studies

Venlafaxine and Venlafaxine ER

 – Assessing Rates and Predictors of Tachyphylaxis During the Prevention of Recurrent Episodes of Depression With Venlafaxine ER for Two Years (PREVENT) Study

 – Desvenlafaxine and Venlafaxine Exert Minimal In Vitro Inhibition of Human Cytochrome P450 and P- Glycoprotein Activities

 – Assessing Rates and Predictors of Tachyphylaxis During the Prevention of Recurrent Episodes of Depression With Venlafaxine ER for Two Years (PREVENT) Study 

 – A Pharmacokinetic Drug-Drug Interaction Study of Venlafaxine and Indinavir 

Vilazodone

 – The Safety and Tolerability Profile of Vilazodone, A Novel Antidepressant for the Treatment of Major Depressive Disorder

Vortioxetine

 – Effective Vortioxetine Dose Varies with Extent of Antidepressant Use Across Countries