In This Issue

Winners & Losers

Dopamine D4 Receptors: Neuropsychiatric Implications

How Have Carve-Outs Changed Managed Behavioral Health Care?

Diagnosis and Treatment of Depression in the Diabetic Patient

Placebo-Controlled Trials in Psychiatric Research: An Ethical Perspective

Ethics and Economics in Placebo-Controlled Trials of New Drugs for Mood Disorders

The Ten Interview: David Shore

Adverse Events Associated With Placebo

Editor’s Letter: Can the Placebo Be the Cure for Depression and Anxiety?

Cover Essay: Boss of Bosses — Charles B. Nemeroff, MD, PhD

Cost & Therapeutics: Chronic Pain