Bipolar Medication, Lamictal, Linked with Serious Immune System Reaction

By | 2018-06-29T07:28:14+00:00 June 29th, 2018|Brief Bulletins from the Field, We Know Psychiatry|

The Food and Drug Administration has issued a warning that the seizure and bipolar medication Lamictal (lamotrigine) can cause a rare but potentially life-threatening immune response. This life-threatening immune response, known as hemophagocytic lymphohistiocytosis (HLH), causes an uncontrolled immune response and can present as a persistent fever greater than 101° F. [...]

Effects of a depression-focused internet intervention in slot machine gamblers: A randomized controlled trial

By | 2018-06-08T16:28:40+00:00 June 8th, 2018|Brief Bulletins from the Field, Featured, We Know Psychiatry|

By Lara Bücker , Julia Bierbrodt, Iver Hand, Charlotte Wittekind, and Steffen Moritz Background Problematic and pathological gambling have been linked to depression. Despite a high demand for treatment and negative financial consequences, only a small fraction of problematic and pathological gamblers seek professional help. The existing treatment gap could be narrowed by providing [...]

Alzheimer’s Therapy Elenbecestat Reduces Brain Amyloid Levels, Trial Shows, but Decline of Clinical Symptoms Still a Question

By | 2018-06-08T08:10:58+00:00 June 8th, 2018|Brief Bulletins from the Field, Featured, We Know Psychiatry|

Treatment with the investigational compound elenbecestat reduced brain amyloid beta levels and was safe and well-tolerated, according to Phase 2 clinical trial results. The presence of amyloid beta plaques is a major characteristic of the brains of Alzheimer’s disease patients. Amyloid beta is produced through the work of a key enzyme called [...]

Esketamine nasal spray prevails in phase 3 trials

By | 2018-06-06T07:29:40+00:00 June 6th, 2018|Brief Bulletins from the Field, We Know Psychiatry|

MIAMI — The combination of an esketamine nasal spray and an oral antidepressant may provide additional benefits for patients with treatment-resistant major depressive disorder, new research suggested. Two posters at a meeting of the American Society of Clinical Psychopharmacology, formerly known as the New Clinical Drug Evaluation Unit meeting, presented [...]

MDMA-Assisted Psychotherapy Improves PTSD

By | 2018-06-05T15:12:24+00:00 June 5th, 2018|Brief Bulletins from the Field, Featured, We Know Psychiatry|

MIAMI — Adding methylenedioxymethamphetamine (MDMA), also known as ecstasy, to intensive psychotherapy appears to relieve posttraumatic stress disorder (PTSD), regardless of the cause, pooled data from six phase 2 studies show. The findings were presented at the American Society of Clinical Psychopharmacology (ASCP) 2018 annual meeting. The pooled data from the [...]

An Alzheimer’s Antibiotic Receives Initial Funding

By | 2018-06-01T09:11:54+00:00 June 1st, 2018|Brief Bulletins from the Field, Featured, We Know Psychiatry|

Alzheimer’s disease startup Cortexyme was able to round up $76 million in funding for a potentially first-in-class treatment, while other companies are looking to move away from the field, according to a posting today on FierceBiotech. The healthy sum comes after the company completed an early safety study of its [...]

News From the APA Convocation: Antipsychotics, Opioids, and PTSD

By | 2018-05-09T13:04:15+00:00 May 9th, 2018|Brief Bulletins from the Field, We Know Psychiatry|

Study Shows Continued Use of Certain Antipsychotics During Pregnancy May Increase Risk of Gestational Diabetes New York, NY. Women who take certain antipsychotic medications and continue the use of these medications through pregnancy may be at increased risk for gestational diabetes, according to new research published online today by the American Journal of [...]

Efficacy of Vortioxetine in Working Patients with GAD

By | 2018-06-01T15:19:29+00:00 May 9th, 2018|Brief Bulletins from the Field, We Know Psychiatry|

Background Vortioxetine is an approved antidepressant that has also demonstrated positive effects on anxiety symptoms in subjects with generalized anxiety disorder (GAD). This post-hoc analysis evaluates the efficacy of vortioxetine in GAD subjects who are working and/or pursuing an education. Methods In study NCT00744627, 301 GAD subjects were randomized to [...]

What’s in a Name? For Some Psychiatrists, a Lot

By | 2018-04-19T09:16:18+00:00 April 18th, 2018|Brief Bulletins from the Field, We Know Psychiatry|

The organization dedicated for decades to "Psychosomatic Medicine" will be rebranded as Consultation-Liaison Psychiatry. The name change, aimed in part at shedding the ambiguity around the word “psychosomatic” and better capturing the mission of consultation-liaison psychiatry, will be reflected across the group’s platforms. The tagline on the group’s journal, Psychosomatics, [...]

Is Methamphetamine-Induced Psychosis Reversible?

By | 2018-01-29T11:21:52+00:00 January 29th, 2018|Brief Bulletins from the Field, We Know Psychiatry|

According to an evidence-based review in the journal Current Psychiatry, the answer is a qualified "Maybe." Chronic methamphetamine use can induce pathological brain changes in the brain. Users can develop thought, mood, and behavioral disorders, including psychosis. Such effects may persist even after extended abstinence. Because cognitive deficits can affect [...]