16 11, 2017

NIMH: Ketamine-Like Hallucinogens May Offer New Hope for Treatment-Resistant Depression

By | 2017-11-16T13:17:35+00:00 November 16th, 2017|Brainscience Blogs|0 Comments

In 2006, psychiatrist Carlos A. Zarate Jr, MD, and colleagues at the National Institute of Mental Health (NIMH) published a seminal finding in Archives of General Psychiatry (now JAMA Psychiatry): A single intravenous dose of ketamine—an anesthetic agent with hallucinogenic properties—produced robust antidepressant effects in patients with treatment-resistant depression (TRD) [...]

15 11, 2017

Digital Tattletales: New Technology Alerts Drug Non-Compliance

By | 2017-11-15T08:03:33+00:00 November 15th, 2017|Brainscience Blogs|0 Comments

The antipsychotic agent, Abilify (aripiprazole, Otsuka), is the first Food and Drug Administration approved digital pill — a medication embedded with a sensor that can tell doctors whether, and when, patients take their medicine. The wearable sensor patch is made by Proteus Digital Health. The approval marks a significant advance in [...]

15 11, 2017

Study Finds Competing Opioid Treatments Same, with One Caveat

By | 2017-11-15T07:41:51+00:00 November 15th, 2017|Brainscience Blogs|0 Comments

A long-awaited study has found that two of the main medications for treating opioid addiction are similarly effective. The study, funded by the federal government, compared Vivitrol, which comes in a monthly shot and blocks the effects of opioids, and Suboxone, which is taken daily in strips that dissolve on the [...]

13 11, 2017

Can an App that Tracks Medication Doses and Mood Swings Help Improve Depression Treatment?

By | 2017-11-13T16:07:19+00:00 November 13th, 2017|Brainscience Blogs|0 Comments

PHARMA NEWS Takeda and Lundbeck are planning a  U.S. test for a depression app that will track mood, in the hopes it will improve depression treatment. The two pharma companies have teamed up with Advocate Health Care on a study that uses an app with a “conversational text interface” to track and [...]

13 11, 2017

Brain Inflammation Tied to Depression and Suicidal Thoughts

By | 2017-11-13T14:57:01+00:00 November 13th, 2017|Brainscience Blogs|0 Comments

On individuals with major depressive disorder (MDD), particularly those who experience suicidal thinking, levels of translocator protein (TSPO), a marker of microglial inflammation, are increased, new research shows. Investigators from the University of Manchester, United Kingdom, found significantly higher levels of TSPO in patients with MDD than in healthy control [...]

13 11, 2017

Effectiveness of Online Collaborative Care for Treating Mood and Anxiety Disorders in Primary Care: A Randomized Clinical Trial

By | 2017-11-13T14:42:05+00:00 November 13th, 2017|Brainscience Blogs|0 Comments

By Bruce L. Rollman, Bea Herbeck Belnap, Biol Hum, Kaleab Z. Abebe Key Points Questions  Is combining an internet support group (ISG) with a care manager–guided computerized cognitive behavioral therapy (CCBT) program better at treating depression and anxiety than CCBT alone and better than primary care physicians’ usual care for these conditions? Findings  Among [...]

6 11, 2017

JAMA Issues Advance Directives for Dementia

By | 2017-11-06T17:57:54+00:00 November 6th, 2017|Brainscience Blogs, Brief Bulletins from the Field|0 Comments

Viewpoint November 6, 2017 Advance Directives for Dementia: Meeting a Unique Challenge By Barak Gaster, Eric B. Larson,  and J. Randall Curtis   In the coming years, an increasing number of people will experience dementia. Worldwide, the number of people living with dementia is projected to increase from 47 million in 2015 to 132 million by [...]

28 10, 2017

Plasticity and Its Association With Working Memory in Patients With Alzheimer Disease

By | 2017-10-28T14:07:01+00:00 October 28th, 2017|Brainscience Blogs|0 Comments

Is dorsolateral prefrontal cortex plasticity impaired in Alzheimer disease? Yes, according to researchers writing in JAMA Psychiatry. Dorsolateral prefrontal cortex plasticity is impaired in Alzheimer disease and is associated with impaired working memory. Findings:  In this cross-sectional study of 32 participants with early Alzheimer disease and 16 healthy control participants, significant [...]

27 10, 2017

News Round-Up: Internet Porn Addiction, Suicide Attempts, Bipolar Disorder in Post-Dementia

By | 2017-10-27T07:29:55+00:00 October 27th, 2017|Brainscience Blogs|0 Comments

Perceived Addiction to Internet Porn Examined Perceived addiction to internet pornography appears to be related strongly to moral scruples around pornography use, both concurrently and over time, rather than with the amount of daily pornography use itself, a recent study found. Participants were adults who had used pornography within the [...]