Alzheimer’s Agent, BAN2401, Shows Promise; Trial Design Hits Snag

By |2018-08-02T07:56:18-07:00August 2nd, 2018|Brief Bulletins from the Field, We Know Psychiatry|

A monoclonal antibody,BAN2401, that targets soluble amyloid-beta oligomers, slowed cognitive decline by up to 47% while clearing brain amyloid in 81% of patients with mild cognitive impairment and very mild Alzheimer’s disease, according to phase 2 study results. A joint venture with Esai and Biogen, BAN2401, is among the most promising [...]

Albuminuria Linked to Increased Risk for Dementia, Cognitive Impairment

By |2021-11-11T17:15:31-08:00December 21st, 2016|Brief Bulletins from the Field, We Know Psychiatry|

Although past research has shown a link between renal dysfunction and cognitive impairment, a new systematic review shows that the presence of albuminuria specifically is also associated with an increased risk of developing cognitive impairment. The meta-analysis of 22 studies, each with at least 100 participants, was carried out to [...]

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