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Two drugs have emerged as the optimal medications for treating insomnia based on the "best-available evidence," but there are caveats. In a comprehensive comparative-effectiveness analysis, lemborexant and eszopiclone showed the best efficacy, acceptability, and tolerability for acute and long-term insomnia treatment. However, eszopiclone may cause substantial side effects — and safety data on lemborexant [...]
Whereas symptoms of depression are known to intensify in patients who have recently experienced an incident stroke, it might also be true in such cases that the depression actually starts to worsen in the months or years before the stroke occurs, suggests a new study of adults 50 years and older. "Stroke seems to [...]
Balovaptan, a novel drug that binds to and blocks vasopressin 1A (V1a) receptors, does not improve social communication in children and adolescents with autism spectrum disorder (ASD), new research shows. Efficacy analysis from a phase 2 trial included more than 160 participants, making it the largest of its kind to date, investigators note. Although [...]
Evidence-Based Psychiatry Combining Medication Adherence Support Plus Long-Acting Injectable Antipsychotic Medication: A Post-Hoc Analysis of 3 Pilot Studies By Thomas Canales, Samuel Rodman, Danette Conklin, Kaylee Sarna, Martha Sajatovic, Jennifer B. Levin
Orally dissolving medications containing buprenorphine are linked to severe dental problems, including total tooth loss, the US Food and Drug Administration (FDA) warns in a safety communication. The oral side effects of these medications, which are used to treat opioid use disorder (OUD) and pain, include cavities/tooth decay, including rampant caries; dental abscesses/infection; tooth [...]
Aaron "Tim" Beck, MD, known as the father of cognitive behavioral therapy (CBT), died on Monday in Philadelphia. He was 100. Beck's pioneering career in psychoanalysis spanned more than seven decades, yielding more than 600 published articles and nearly two dozen books. His development of CBT redefined the practice of [...]
An investigational, orally dissolving film formulation of dexmedetomidine (BXCL501, BioXcel Therapeutics) may offer rapid relief from acute agitation related to schizophrenia or bipolar disorder (BD), results of two phase 3, randomized, placebo-controlled trials show. Dr Leslie Citrome For both disorders, BXCL501 showed "superiority over placebo" by meeting the primary endpoint of reduction of agitation as [...]
From: JAMA Psychiatry. Published online October 16, 2020. doi:10.1001/jamapsychiatry.2020.3746 By Christine Moutier, MD Introduction International and US experts on suicide have expressed concerns about the potential the coronavirus disease 2019 (COVID-19) pandemic has to increase the risk of suicide through its effects on a number of well-established suicide risk factors.1,2 Suicide surveillance [...]
According to the a survey conducted by the a prominent medical association, living in the United States in 2020 is a stressful experience, even for the most even-keeled among us. And the impending political contest ranks high on the list of factors keeping us up at night. A survey conducted [...]
General Psychiatry Cariprazine to Treat Schizophrenia and Bipolar Disorder in Adults By Amber Edinoff, Miriam T. Ruoff, Yahya T. Ghaffar, Arthur Rezayev, Devanshi Jani, Adam M. Kaye, Elyse M. Cornett, Alan D. Kaye, Omar Viswanath, Ivan Urits
General Psychiatry Asenapine Transdermal Patch for the Management of Schizophrenia By Maxine Zhou, Sahar Derakhshanian, Alexander Rath, Sarah Bertrand, Caroline DeGraw, Rachel Barlow, Aja Menard, Adam M. Kaye, Jamal Hasoon, Elyse M. Cornett, Alan D. Kaye, Omar Viswanath, Ivan Urits
General Psychiatry Lumateperone for the Treatment of Schizophrenia By Amber Edinoff, Natalie Wu, Charles deBoisblanc, Catherine Olivia Feltner, Mariah Norder, Vesela Tzoneva, Adam M. Kaye, Elyse M. Cornett, Alan D. Kaye, Omar Viswanath, Ivan Urits
General Psychiatry Use of Clozapine in the General Hospital By Feras Ali Mustafa
General Psychiatry Antiepileptic Drugs and Bone Health: Current Concepts By Antonio Siniscalchi, Sean Murphy, Erika Cione, Leonardo Piro, Giovambattista De Sarro, Luca Gallelli
General Psychiatry Psychiatric Prescribing Patterns for Depression Treatment in an Outpatient Depression Clinic By Roberta E. Wilson, Sarah J. Choi, Sagar V. Parikh, Jolene R. Bostwick
This product is the full issue of Psychopharmacology Bulletin VOL 49 No. 2. Upon purchase, you will receive a single downloadable PDF file with all this issues articles stacked from front cover to back cover.
