This handbook is meant to provide quick, bed- side, basic information about currently approved anticancer and chemoprotectant agents. Drug indications approved by the US Food and Drug Administration (FDA) are included to provide a framework for deciding use of that agent. However, anticancer agents are often used outside of FDA labeling and sometimes used based on minimal clinical data. In this situation, the dosage guidelines will provide an estimate for a safe dose to use in a particular patient, especially with regard to the total to be administered per cycle or treatment course. To prevent errors though, the original refer- ence source for use of that agent or combination should always be consulted first.