Surveying the Field of Gynecologic Oncology
By William J. Hoskins, MD
Letter From the Editors
Addressing the Quality Chasm for a New Health System in the 21st Century
By J. Lyle Bootman, PhD, and Daniel D. Von Hoff, MD
Palliative Chemotherapy for Advanced Colorectal Cancer
By Peter Simmonds, FRACP, and Tim Iveson, MD
Our Current Understanding of Genetic Alterations in Colorectal Cancer, and Implications for Clinical Use
By Manel Esteller, MD, PhD, and Montserrat Sanchez-Cespedes, PhD
Flavonoids Join the War on Cancer
By Uwe Wenzel, PhD
Pharmacy Practice
Oral Chemotherapy for Colorectal Cancer: An Update
By Sunil Sharma, MD
In Vitro Tests to Predict Human Tumor Sensitivity to Cytotoxic Agents
By Axel-R. Hanauske, MD, PhD
An Update on Cancer Chemoprevention
By Tammy Chernin, RPh
Letter From the Editors: A Question of Ownership
By Daniel D. Von Hoff, MD, and J. Lyle Bootman, PhD
Critical Analysis of Recent Phase III Studies for the Treatment of Colorectal Cancer Implications for Future Clinical Trial Design
DISCUSSANTS: John S. Macdonald, MD, Richard Goldberg MD, Leonard B. Saltz, MD, Daniel G. Haller, MD,
and Richard Simon, DSc
Metastasis-Suppressor Genes: A Review and Perspective on an Emerging Field
By Barbara A. Yoshida, Mitchell M. Sokoloff, Danny R. Welch, and Carrie W. Rinker-Schaeffer
Sequential Chemotherapy for the Curative Treatment of Squamous Cell Cancer of the Head and Neck: A New Paradigm
By Marshall R. Posner, MD
Monitoring Chemotherapy in an Aging Population
By Judith A. Smith, Pharm.D, BCOP
Are We Prepared for the Genomics Era?
By J. Lyle Bootma
The Genetics of Multiple Myeloma
By Brian Van Ness, PhD
High-Dose Therapy in Patients with Multiple Myeloma
By Bhawna Sirohi, MBBS, DCH and Ray Powles, MD, MRCP, MRCPath
Pharmacology and Therapeutic Use of Trastuzumab in Breast Cancer
By Imad Treish, PharmD, Rowena Schwartz, PharmD, BCOP, and Celeste Lindley, PharmD, BCPS, FASHP, FCCP
Guest Editor
Research Needs in Myeloma
Gregory R. Mundy, MD
Colorectal Cancer Screening: How Are We Doing and How Can We Improve?
Virender K. Sharma, MD, and Colin W. Howden, MD
Increased Mortality Risk Associated With Medial Breast Tumors May Be Due to Untreated Internal Mammary Node Metastases
Caroline Lohrisch, MD