Salt Lake City, UT — Lipocine Inc. announced positive progress in its pivotal phase 3 clinical trial evaluating oral brexanolone (LPCN 1154) for the treatment of postpartum depression (PPD). The…
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Bristol Myers Squibb announced that the US Food and Drug Administration (FDA) has granted Fast Track Designation to BMS-986446, a potential best-in-class anti–microtubule binding region tau (anti–MTBR-tau) antibody currently in…
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What if the next leap in psychiatric treatment doesn’t come from tweaking dopamine or serotonin, but from reengineering the immune system, harnessing neuroplasticity, or refining orexin antagonism? In 2025, the…
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By mid-2025, the psychopharmacology landscape feels paradoxical: on one hand, deeply familiar challenges — slow response, heterogeneity, side effects — still dominate clinical reality. On the other, a wave of…
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What if the next leap in psychiatric therapeutics comes not from entirely new receptors, but from smarter targeting—or smarter delivery? From LSD-derived anxiety relief to once-weekly schizophrenia pills, this week’s…
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Key Updates Biomarker-Stratified Antidepressant ResponseA randomized trial in JAMA Psychiatry (Sept 2025) found that patients with treatment-resistant depression who carried the ANK3 biomarker had improved outcomes with liafensine, suggesting potential…
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From Psychedelics to Mechanism-Driven Precision: Recent Shifts in Depression Treatment What if we could reliably predict which antidepressant will work for a patient before waiting four weeks of trial-and-error? As…
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Recent changes in the legal landscape in the United States have affected access to abortion, and this restricted access has profound effects on both physical and mental health of reproductive-aged…
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The FDA’s Psychopharmacologic Drugs Advisory Committee is evaluating a New Drug Application (NDA) for a combination of brexpiprazole and sertraline as a potential treatment for posttraumatic stress disorder (PTSD). If…
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Johnson & Johnson recently announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for lumateperone (Caplyta®), based on long-term data supporting…
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A study of 1.5 million UK adults found that autoimmune diseases are linked to a nearly twofold increase in the risk for mood disorders such as depression, anxiety, and bipolar…
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Semaglutide, a medication for type 2 diabetes (T2D), is associated with a 20%-46% reduced risk for Alzheimer's disease-related dementia compared with other antidiabetic drugs. A study analyzed electronic health records…
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An international panel of 89 experts from 17 countries has developed new guidelines—Reporting of Setting in Psychedelic Clinical Trials (ReSPCT)—to standardize how psychedelic clinical trials report 'set and setting,' the…
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A Phase 3 clinical trial has shown that LYN-005—a once-weekly oral capsule formulation of risperidone—achieves comparable bioavailability and symptom control to daily dosing in patients with schizophrenia or schizoaffective disorder.…
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Psychological therapy has been shown to significantly alleviate depression and anxiety in stroke survivors, particularly when initiated within six months of the stroke event. In a study involving over 7,000…
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Synthetic psilocybin demonstrates a significant reduction in treatment-resistant depression symptoms
A Phase 3 clinical trial of COMP360, a synthetic formulation of psilocybin, showed a significant reduction in symptoms of treatment-resistant depression. Conducted at 32 sites across the U.S. with 258…
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Two new studies examining mental health risks postpartum were published online in the American Journal of Psychiatry in conjunction with Maternal Mental Health Awareness Month and the 2025 Annual Meeting…
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A novel blood test that detects a key biomarker for Alzheimer’s disease (AD) could help physicians more accurately determine the presence and track disease progression. The test measures levels of…
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Neurocrine Biosciences presented new data from the long-term, open-label KINECT 4 study demonstrating remission of tardive dyskinesia (TD) among most patients treated with once-daily valbenazine (Ingrezza) capsules, at the 2025…
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Objective Postpartum depression (PPD), now referred to as perinatal depression, is a prevalent and debilitating mood disorder that reduces health-related quality of life (HRQoL) and psychosocial functioning. Esketamine, which is…
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Objective Many psychotropic drugs are highly associated with related weight gain. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are established anti-obesity and glucose-lowering agents. Preliminary evidence also indicates they are fit for…
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Background In VIVRE (NCT04448431), vortioxetine was associated with significantly higher rates of symptomatic and functional remission, better daily and social functioning, and greater treatment satisfaction than desvenlafaxine in patients with…
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According to a brief on Medscape, supported by the NIH, The use of general anesthesia during cesarean deliveries is associated with an increased risk for postpartum depression (PPD) that necessitates…
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Writing in Psychopharmacology Bulletin, Trishna Sharma, Annette C. Kestner and Abhishek Reddy described a 17-year-old female with a history of NT1 and no past psychiatric history presented to the hospital…
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Writing in Psychopharmacology Bulletin, authors Chinenye Okoro, Kaye Homer, Marlene Kelbrick, Jonny Walker, Mary Sam, Justine Burge, Rosie Richards, Gabriela Paduret, and Feras Ali Mustafa examined a 53-year-old Caucasian female…
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Ahmed Naguy, Nadyah Alayadhi, Saxby Pridmore, Bibi Alamiri, writing in Psychopharmacology Bulletin, made the following observations: An 11-year-old male Qatari boy was brought in to hospital by his parents for…
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Salt is found in nearly every kitchen across the world; however, it is not typically thought of to be a means for suicide. Depending on the age and size of…
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Crisis support lines are currently undergoing testing of artificial intelligence (AI) to assess the quality of their response. These support lines rely on well-trained counselors who are adept at handling…
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According to the American Psychiatric Association's annual poll, 70% of adults in the United States report feeling anxious or extremely anxious about their own and their family's safety. This number…
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According to published reports, The US Food and Drug Administration (FDA) has granted Breakthrough Device designation to Sooma Medical's portable, noninvasive neuromodulation device for treating depression, which can be administered…
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Objective: To compare the efficacy and speed of achieving remission/response in treatment-resistant depression (TRD) patients treated with subanesthetic intravenous (IV) ketamine and intranasal (IN) esketamine approved by the US Food…
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In a phase 2 study, pimavanserin showed promise as a treatment for major depressive disorder (MDD) when used in combination with other antidepressants. Two phase 3 studies were then conducted…
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The US Food and Drug Administration (FDA) has approved the anti-amyloid beta protofibril antibody lecanemab (Leqembi, Eisai) for the treatment of early Alzheimer's disease (AD). The agency approved the treatment…
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In a study published in PLOS Medicine that uses data spanning 25 years, the authors observed short sleep duration to be associated with risk of chronic disease and subsequent multimorbidity…
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An enzyme that efficiently degrades and metabolizes cocaine has been given a ‘cooperative agreement grant’ from the National Institute on Drug Abuse (NIDA) part of the National Institutes of Health.…
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It is known that psychedelics activate serotonin 2A receptors, which eventually leads to states like increased empathy and out-of-body experiences. One of the key questions remaining n psychedelic medicine is…
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Suicidal behaviors were higher during the school year (average of 6,761/month) compared to school break (average of 4,512/month). Prevalence of suicidal behaviors was highest in October for both hospitalization and…
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Two drugs have emerged as the optimal medications for treating insomnia based on the "best-available evidence," but there are caveats. In a comprehensive comparative-effectiveness analysis, lemborexant and eszopiclone showed the best efficacy, acceptability, and…
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Whereas symptoms of depression are known to intensify in patients who have recently experienced an incident stroke, it might also be true in such cases that the depression actually starts to worsen in…
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Balovaptan, a novel drug that binds to and blocks vasopressin 1A (V1a) receptors, does not improve social communication in children and adolescents with autism spectrum disorder (ASD), new research shows. Efficacy analysis from a…
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In a continuation of bad news for investigative Alzheimer's drugs, Roche has halted five early and midstage trials covering a range of therapeutic categories, including Alzheimer's drugs. The Swiss pharma…
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Sage and Biogen’s depression drug quickly relieved symptoms of depression in a phase 3 trial, but the readout did little to quell concerns about the med’s durability of effect, an…
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We are frequently consulted by patients with treatment resistant depression (TRD).Reference Fogelson and Leuchter1 Many of these patients have never met criteria for a manic episode so they are not diagnosed…
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No pharmacological agents are approved by the U.S. Food and Drug Administration (FDA) to treat dementia-related psychosis (DRP). Pimavanserin, an atypical antipsychotic that acts as a selective serotonin inverse agonist/antagonist…
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The federal government on Thursday proposed new guidelines for prescribing opioid painkillers that remove its previous recommended ceilings on doses for chronic pain patients and instead encourage doctors to use…
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Valid assessment of drug efficacy and safety requires an evidence base free of reporting bias. Using trial reports in Food and Drug Administration (FDA) drug approval packages as a gold…
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A group of researchers aimed to determine the risks of premature mortality and suicide in people with common noncommunicable diseases, with and without psychiatric disorder comorbidity. In this longitudinal study…
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ORIGINAL RESEARCH Doxepin for Insomnia: Executive Function before and after Treatment By Zhenghe YU, Li HAN, Pan YAN, Wenjuan LIU, Lishan REN, You XU, Lili YANG, Lisha MA, Youdan WEI,…
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Orally dissolving medications containing buprenorphine are linked to severe dental problems, including total tooth loss, the US Food and Drug Administration (FDA) warns in a safety communication. The oral side effects of these medications,…
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Aaron "Tim" Beck, MD, known as the father of cognitive behavioral therapy (CBT), died on Monday in Philadelphia. He was 100. Beck's pioneering career in psychoanalysis spanned more than seven…
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The antidepressant fluvoxamine (Luvox) may prevent hospitalization and death in outpatients with COVID-19, new research suggests. Results from the placebo-controlled, multisite, phase 3 TOGETHER trial showed that in COVID-19 outpatients at high…
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The US Food and Drug Administration (FDA) has approved a high-dose naloxone injection product for the emergency treatment of opioid overdose. ZIMHI from Adamis Pharmaceuticals is administered using a single-dose,…
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Johnson & Johnson thinks a longer-acting treatment against schizophrenia will help keep patients on their prescriptions and reduce their chances of a relapse. Now, with a FDA nod under its…
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Background Precise cannabis treatment dosing remains a major challenge, leading to physicians’ reluctance to prescribe medical cannabis. Objective To test the pharmacokinetics, analgesic effect, cognitive performance and safety effects of…
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The objective of this research was to develop and evaluate an evidence-based suicide attempt risk checklist to aid clinicians in the identification of individuals at risk for attempting suicide in…
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I cut myself for the first time today and I feel worse I'm up at 5 am writing this because I can't sleep and anxiety is keeping me up. I'm…
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According to well-placed recent reports, Biogen Inc withdrew its paper that analyzed results from the clinical trials of its controversial Alzheimer's drug, Aduhelm, that was submitted to medical journal JAMA.…
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There are multiple risk factors for self-harm, including a history of abuse, trauma, physical and mental illness, and bullying. Identifying these factors is a key part of prevention, ensuring that…
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Three members of a US Food and Drug Administration (FDA) advisory committee are explaining why they do not support approval of the drug aducanumab (Biogen, Eisai) for the treatment of…
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An investigational, orally dissolving film formulation of dexmedetomidine (BXCL501, BioXcel Therapeutics) may offer rapid relief from acute agitation related to schizophrenia or bipolar disorder (BD), results of two phase 3, randomized, placebo-controlled trials show. Dr…
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Cannabis sativa has a long history of use both as a textile and as an intoxicant used for medicinal, spiritual, and recreational purposes. California voted to regulate cannabis for medical…
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SUMMARY In this study, we observed that compared to women with no prior cancer, breast cancer survivors had higher risk of anxiety, depression, sleep problems, sexual dysfunction, fatigue, receipt of…
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From: JAMA Psychiatry. Published online October 16, 2020. doi:10.1001/jamapsychiatry.2020.3746 By Christine Moutier, MD Introduction International and US experts on suicide have expressed concerns about the potential the coronavirus disease 2019 (COVID-19)…
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Chronic use of antiepileptic drugs (AEDs) can induce the development of adverse effects on bone metabolism. In epileptic patients treated with AED, the monitor- ing of biochemical markers of bone…
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ABSTRACT ~ Objective: Off-label use of prazosin for posttraumatic stress disorder-related sleep disturbances (PTSD-SD) is widespread in Veterans Health Administration (VA) settings, but clinical trials have had mixed results. Trial…
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ABSTRACT ~ Objectives: To sequentially study the effectiveness of lithium and divalproex monotherapy and adjunctive therapy with quetiapine or lamotrigine in the acute and continuation treatment of bipolar I or…
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Although currently available antidepressants increase monoamine levels soon after the start of treatment, therapeutic benefits are often delayed by several weeks and the majority of patients with major depressive disorder…
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A novel, noninvasive, over-the-counter electromagnetic neuromodulation device (ActiPatch, BioElectronics Corp.) appears to deliver long-lasting relief in chronic pain patients. Results of a long-term prospective study that included 240 patients who…
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Daily intranasal insulin may be effective in slowing progression of mild cognitive impairment (MCI) or Alzheimer's disease (AD), new research suggests. The findings were presented at the Alzheimer's Association International…
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According to evidence-based reviews, the answer is a qualified “Maybe.” Chronic methamphetamine use can induce pathological brain changes in the brain. Users can develop thought, mood, and behavioral disorders, including psychosis.…
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Patients with prostate, bladder or kidney cancers are at greater risk of dying if they have had psychiatric care prior to the cancer treatment. In addition, patients with these cancers…
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Biogen and Eisai have announced that they are discontinuing the ENGAGE and EMERGE trials, which were designed to test the efficacy and safety of aducanumab in patients with mild cognitive…
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The US Food and Drug Administration (FDA) has approved brexanolone intravenous infusion (Zulresso, Sage Therapeutics), the first-ever drug indicated for the treatment of postpartum depression. The drug is administered under medical…
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Adding the Alzheimer drug memantine (Namenda, Allergan) to treatment with a selective serotonin reuptake inhibitor may improve depressive symptoms, executive function, and other outcomes in older patients with both depression…
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The Food and Drug Administration yesterday approved an intranasal form of esketamine for treatment-resistant depression in adults who have failed at least two oral antidepressants of different classes. The spray, from…
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A preliminary study of five patients suffering from both depression and substance abuse disorders suggest that isn’t the case. The study was published Jan. 9 in the journal JAMA…
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Furthering the role of immune system disorders in the development of mental disorders, recent research links infections that children contract during their childhood with increased risk of mental disorders during…
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A new dosage strength of buprenorphine and naloxone sublingual film was approved recently by the Food and Drug Administration. Cassipa sublingual film, made by Teva Pharmaceuticals, is a 16 mg/4…
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A front page New York Times story read, “Every year, thousands of people addicted to opioids show up at hospital emergency rooms in withdrawal so agonizing it leaves them moaning…
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Conclusions The overall increase in prevalence rates of BZD dispensations during the study period and the unexpectedly high proportion of individuals who were prescribed a BZD on a long-term basis…
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A monoclonal antibody,BAN2401, that targets soluble amyloid-beta oligomers, slowed cognitive decline by up to 47% while clearing brain amyloid in 81% of patients with mild cognitive impairment and very mild Alzheimer’s…
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The Food and Drug Administration has issued a warning that the seizure and bipolar medication Lamictal (lamotrigine) can cause a rare but potentially life-threatening immune response. This life-threatening immune response,…
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By Lara Bücker , Julia Bierbrodt, Iver Hand, Charlotte Wittekind, and Steffen Moritz Background Problematic and pathological gambling have been linked to depression. Despite a high demand for treatment and negative financial consequences, only…
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Treatment with the investigational compound elenbecestat reduced brain amyloid beta levels and was safe and well-tolerated, according to Phase 2 clinical trial results. The presence of amyloid beta plaques is a major…
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MIAMI — The combination of an esketamine nasal spray and an oral antidepressant may provide additional benefits for patients with treatment-resistant major depressive disorder, new research suggested. Two posters at…
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MIAMI — Adding methylenedioxymethamphetamine (MDMA), also known as ecstasy, to intensive psychotherapy appears to relieve posttraumatic stress disorder (PTSD), regardless of the cause, pooled data from six phase 2 studies…
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Alzheimer’s disease startup Cortexyme was able to round up $76 million in funding for a potentially first-in-class treatment, while other companies are looking to move away from the field, according…
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By Sofia Medrano, Amal Abdel-Baki, Emmanuel Stip, and Stéphane Potvin Abstract Poor adherence to antipsychotics, which affects outcome, is frequent in first episode psy- chosis (FEP). Most randomized studies demonstrate no superiority…
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By Marcela Almeida and Heather Burrell-Ward To the editor, We read with great interest the article by S. Thippaiah and colleagues in a recent issue of the journal. The authors reported…
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Prescription Stimulant Use, Misuse, and Motivations Approximately 16 million US adults used prescription stimulants in the preceding year (annual average), 5 million misused prescription stimulants without use disorders, and 0.4…
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Study Shows Continued Use of Certain Antipsychotics During Pregnancy May Increase Risk of Gestational Diabetes New York, NY. Women who take certain antipsychotic medications and continue the use of these medications through…
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Background Vortioxetine is an approved antidepressant that has also demonstrated positive effects on anxiety symptoms in subjects with generalized anxiety disorder (GAD). This post-hoc analysis evaluates the efficacy of vortioxetine…
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Autism Researchers at University of California San Diego School of Medicine are preparing a first-of-its-kind, multidisciplinary investigation to determine if and how cannabidiol (CBD), a non-psychoactive compound found in the…
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By Sereen Rose Thomson, Navin Patil, Balaji Ommurugan, and Rajesh Krishna Bhandary Abstract Schizophrenia treatment needs to cover several psychological interventions and pharmacological treatment for stabilizing the disease course and decreasing relapses. Sexual side…
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By Johan Y. Cohen and Amélie Guilbault Abstract Due to the stringent regulatory environment for therapeutics, common side-effects of drugs in the general population are largely well-documented. This is however…
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By Jacquelin Peck, MD, and Omar Viswanath, MD ABSTRACT Optimal management of chronic pain is complex and often daunting. In the pediatric and adolescent population, care-givers face additional biases in the…
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A new study by the medical historian, Herwig Czech, has shed more light on the revelations that Hans Asperger, the Austrian pediatrician for whom a form of autism is named,…
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The organization dedicated for decades to "Psychosomatic Medicine" will be rebranded as Consultation-Liaison Psychiatry. The name change, aimed in part at shedding the ambiguity around the word “psychosomatic” and better…
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Children with comorbid autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are at an increased risk of anxiety and mood disorders, a cross-sectional analysis has shown. “Our study supports that…
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A more powerful ketamine (esketamine) nasal spray, combined with standard-of-care treatment, shows promise in quickly tamping-down depressive symptoms, according to results of a phase 2 study published April 16 in the…
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For Immediate Release April 10, 2018 Los Angeles CA www.medworksmedia.com Psychopharmacology Bulletin DIGITAL ISSN: 2472-2448; PRINT ISSN: 0048-5764 From: Michael E. Thase, MD, Editor-in-Chief James La Rossa Jr., Editorial Director…
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We are excited to announce that MedWorks Media's flagship journal, Psychopharmacology Bulletin, has been featured in EBSCO's latest issue of New & Notable. MedWorks Media (Psychopharmacology Bulletin) has partnered with…
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Gabapentin’s anxiolytic and sedative properties along with its overall safety profile suggest that it may be a viable adjuvant to lorazepam in the management of acute alcohol withdrawal. By Christopher…
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In what may be the first foray by Big Pharma into the sale of medical marijuana products, Novartis has struck a deal with a Canadian company that sells medical cannabis…
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The US Food and Drug Administration (FDA) has approved a supplemental new drug application for lurasidone (Latuda) for the treatment of major depressive episodes associated with bipolar I disorder (bipolar…
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In a fascinating note in today's Journal of the American Medical Association (JAMA), Robert M. Post of the George Washington University School of Medicine attributes stigma as one of the main factors…
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Top 5 Articles of February 2018 Updated for 2018 Dosing and Monitoring: Child and Adolescent Psychotropic Criteria For Children And Adolescents Psychotropic Drugs: Side Effects And Teratogenic Risks Recommended Clinical…
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The increase in risk for alcohol use disorder (AUD) in a married individual following a diagnosis of alcoholism in the other spouse is "large and rapid," according to researchers writing…
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By JoAnn E. Manson, and Shari S. Bassuk Dietary supplementation is approximately a $30 billion industry in the United States, with more than 90 000 products on the market. In recent national surveys, 52%…
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According to an evidence-based review in the journal Current Psychiatry, the answer is a qualified "Maybe." Chronic methamphetamine use can induce pathological brain changes in the brain. Users can develop…
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By Robin Stevenson, and Donald E. Moore Jr. Medical education is a continuum of 3 parts; undergraduate medical school education, postgraduate training, and continuing medical education (CME). CME differs from the other 2 educational components…
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Eli Lilly had hoped that EXPEDITION3 would prove to the world that amyloid beta was the cause of Alzheimer’s and that solanezumab could bend the curve of cognitive decline back…
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By Sheila Gupta, Tiffany Phalen, and Sanjay Gupta There is a need for additional treatment options to improve symptoms, enhance the quality of life (QOL), and reduce suffering among patients who have chronic…
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NEW YORK (Thomson Reuters Foundation) - Depression and anxiety afflict Americans who are concerned with the fate of the environment, according to a study of the mental health effects of…
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Hawaii, Vermont, Connecticut and Utah Round-Out Top Mississippi, Louisiana, Arkansas, Alabama, and West Virginia Bottom-Out List A year of surprises ended with one more bit of unexpected news: Massachusetts, not Hawaii,…
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Taking folic acid and/or multivitamin supplements preceding and during pregnancy is associated with a lower risk of offspring developing autism spectrum disorder (ASD), an observational epidemiologic study published Jan. 3…
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Demographics Remain Relatively Unchanged – Middle Aged White Men at Greatest Risk The CDC recently released the most recent data related to suicide for the year 2016. According to these…
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The prevalence of autism spectrum disorder (ASD) in U.S. children and adolescents climbed to 2.41% from 2014 to 2016, Guifeng Xu, MD, and her associates, wrote in a research letter.…
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Attention Bias, Threat/Anxiety Symptoms Linked A recent study indicates associations between threat bias and pediatric anxiety symptoms, and suggests that vigilance to external threats manifests more prominently in symptoms of…
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Cannabidiol linked to reduction in psychotic symptoms in schizophrenia Patients with schizophrenia showed signs of improvement in positive psychotic symptoms and clinician-rated improvement after treatment with cannabidiol, a component of…
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CDC researchers find > 50% of people in 10 states who died of opioid overdoses during the second half of 2016 tested positive for fentanyl. Researchers examined 5,152 people who…
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A new study, published in the open-access journal Frontiers in Human Neuroscience shows that older people who routinely partake in physical exercise can reverse the signs of aging in the brain,…
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Written by Dr. Bruce Kehr Psychiatrists are using genetic testing to determine which prescription medications work best for treating each patient’s particular addiction. For example, doctors can test patients who…
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The FDA plans to convene an expert panel to examine the population-level effects of treating opioid addiction with medication in hopes of gaining wider acceptance of and insurance coverage for…
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The Food and Drug Administration has approved an extended-release, subcutaneous injection formulation of buprenorphine for use in treating moderate to severe opioid use disorder (OUD), the manufacturer of the drug…
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By Michael J. Manos, Kimberly Giuliano, and Eric Geyer The Affordable Care Act of 2010 sought to transform medical care in the United States from procedures to performance, from acute episodes of…
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An investigational Alzheimer’s drug intended to potentiate acetylcholine release didn’t pass muster in a global phase 3 study, despite a successful phase 2 trial. Intepirdine on a background of stable-dose donepezil…
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SAN FRANCISCO (Reuters) - Facebook Inc will expand its pattern recognition software to other countries after successful tests in the U.S. to detect users with suicidal intent, the world's largest…
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Allergan plc has announced that the US Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for Vraylar (cariprazine) for the maintenance treatment of adults with…
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In 2006, psychiatrist Carlos A. Zarate Jr, MD, and colleagues at the National Institute of Mental Health (NIMH) published a seminal finding in Archives of General Psychiatry (now JAMA Psychiatry):…
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The antipsychotic agent, Abilify (aripiprazole, Otsuka), is the first Food and Drug Administration approved digital pill — a medication embedded with a sensor that can tell doctors whether, and when, patients…
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A long-awaited study has found that two of the main medications for treating opioid addiction are similarly effective. The study, funded by the federal government, compared Vivitrol, which comes in a…
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PHARMA NEWS Takeda and Lundbeck are planning a U.S. test for a depression app that will track mood, in the hopes it will improve depression treatment. The two pharma companies have…
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On individuals with major depressive disorder (MDD), particularly those who experience suicidal thinking, levels of translocator protein (TSPO), a marker of microglial inflammation, are increased, new research shows. Investigators from…
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By Bruce L. Rollman, Bea Herbeck Belnap, Biol Hum, Kaleab Z. Abebe Key Points Questions Is combining an internet support group (ISG) with a care manager–guided computerized cognitive behavioral therapy (CCBT) program better at…
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Longer Lives, Better Living By Bill Gates In every part of the world, people are living longer than they used to. Thanks to scientific advancements, fewer people die young from…
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Viewpoint November 6, 2017 Advance Directives for Dementia: Meeting a Unique Challenge By Barak Gaster, Eric B. Larson, and J. Randall Curtis In the coming years, an increasing number of people will experience dementia. Worldwide,…
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Is dorsolateral prefrontal cortex plasticity impaired in Alzheimer disease? Yes, according to researchers writing in JAMA Psychiatry. Dorsolateral prefrontal cortex plasticity is impaired in Alzheimer disease and is associated with impaired…
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Perceived Addiction to Internet Porn Examined Perceived addiction to internet pornography appears to be related strongly to moral scruples around pornography use, both concurrently and over time, rather than with…
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October 26, 2017 www.medworksmedia.com From: Michael E. Thase, MD, Editor-in-Chief & James M. La Rossa Jr., Editorial Director & Publisher — The Most Advanced Search Engine in Psychopharmacology — Comprehensive…
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Alan F. Schatzberg, MD Madness Rising Research into Hallucinogens Gives Hope to the Hopeless and Fuels a Drug Epidemic: A Tale of Two Disparate Worlds By James M. La…
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Original Investigation Association of Lithium in Drinking Water With the Incidence of Dementia Lars Vedel Kessing, Thomas Alexander Gerds, Nikoline Nygård Knudsen, Lisbeth Flindt Jørgensen, Søren Munch Kristiansen, Denitza Voutchkova, Vibeke Ernstsen, Jörg Schullehner, Birgitte Hansen, Per Kragh Andersen, Annette Kjær Ersbøll Question Is…
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Psychopharmacology Bulletin, V47, N3: Links to In-Depth Articles ORIGINAL PRESENTATIONS Baseline Demographics and Characteristics From a Paliperidone Palmitate Study in Subjects with Recent-Onset Schizophrenia or Schizophreniform Disorder. By…
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This work was sponsored by a Young Investigator Grant from the American Foundation for Suicide Prevention (AFSP) BACKGROUND Suicide is preventable, yet still remains a worldwide cause of death in…
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The US Food and Drug Administration (FDA) has approved a new formulation of methylphenidate for children with attention-deficit/hyperactivity disorder (ADHD). Cotempla XR-ODT (Neos Therapeutics Inc) is the first and only…
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By Megan Brooks BOSTON — Sleep-disordered breathing (SDB) may play a role in persistent depressive symptoms and poor response to standard pharmacologic treatments in adolescents, new research suggests. Screening adolescents with…
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By Nassir Ghaem Wide-Ranging Benefits At the recent American Psychiatric Association annual meeting in San Diego, an update symposium was presented on the topic of "Lithium: Key Issues for Practice." In…
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Original Investigation By Jari Tiihonen, MD, Ellenor Mittendorfer-Rutz, Maila Majak; et al Key Points Question Are there any clinically meaningful differences between specific antipsychotic medications or routes of administration regarding the risk of psychiatric…
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MIAMI – Medications in development for the treatment of attention-deficit/hyperactivity disorder (ADHD) target specific behaviors, such as impulsive aggression, and genes that involve the glutamatergic network, new research shows. In…
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New Insight Into Off-Label Ketamine Use for Depression By Nancy A. Melville MIAMI – As the off-label use of ketamine for the treatment of severe depression continues to soar, two…
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Anne Katrine Pagsberg , Pia Jeppesen, Dea Gowers Klauber, Karsten Gjessing Jensen, Ditte Rudå, Marie Stentebjerg-Olesen, Peter Jantzen, Simone Rasmussen, Eva Ann-Sofie Saldeen, Britt Glenn Lauritsen, Niels Bilenberg, Anne Dorte Stenstrøm, Louise Nyvang , Sarah Madsen, Thomas M Werge, Theis Lange ,Christian Gluud, Maria Skoog, Peter Winkel, Jens Richardt, M Jepsen, Birgitte…
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From Depths of Addiction to Triumph of Recovery: ABC Journalist Shares Story of Strength and Inspiration Elizabeth Vargas , who delivered the 2017 William C. Menninger Memorial Award Lecture Monday…
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SAN DIEGO, May 22, 2017 – Many Americans have been directly touched by the opioid crisis — more than a quarter of Americans and more than a third of…
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Americans Favor Treatment, Not Enforcement, to Address Opioid Crisis; Many Americans Believe Access to Illegal Opioids and Painkillers is Easy; One in Five Millennials Think it’s OK to Share…
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SAN DIEGO, May 20, 2017 – Cyberbullying may exacerbate mental health conditions among adolescents, particularly teens who have experienced previous emotional abuse, according to new research presented at the…
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SAN DIEGO, May 20, 2017 – Adolescents who were highly exposed to natural and environmental disasters show higher levels of alcohol misuse and emotional trauma than their peers, according…
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The New York Times recently reported that Three-fifths of troops discharged from the military for misconduct in recent years had a diagnosis of post-traumatic stress disorder, traumatic brain injury or…
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By Benjamin W. Chaffee , Elizabeth T. Couch, Stuart A. Gansky Objectives Evaluate trends from 2011–2015 in electronic cigarette (e-cigarette) use among U.S. adolescents, grades 6–12, including prevalence and associations…
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By Maria R. Restivo , Margaret C. McKinnon, Benicio N. Frey, Geoffrey B. Hall, Wasimuddin Syed, Valerie H. Taylor In a research article published in the Open Access journal PLOS,…
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The prospect of millions of people unable to afford coverage led to an outcry from the health care industry as well as consumer groups. They found an uncommon ally in…
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The Achilles Heel of psychiatry has always been the public's distrust of what defines a mental disorder and whether it can be treated effectively. Oftentimes, not until a trusted public…
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Berk Ustun, Lenard A. Adler, Cynthia Rudin, et al Key Points Question Can a brief screening scale based on patient responses to structured questions detect DSM-5 adult attention-deficit/hyperactivity disorder in…
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Richard J. Kryscio, Erin L. Abner, Allison Caban-Holt, et al. Key Points Question Can vitamin E or selenium prevent dementia in asymptomatic older men? Findings The Prevention of Alzheimer’s Disease…
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Treatment with the diuretic bumetanide (Bumex, Validus) improved core symptoms of autism spectrum disorder (ASD), including social deficits and stereotyped behaviors, results from a multicenter phase 2b study show. Bumetanide…
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The New York Times today reported that researchers writing for the journal, Nature, found that There are now thousands of fake open-access journals, about as many as legitimate ones. The…
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In findings reported in a letter to the editor published online March 10 in Schizophrenia Research and reported by Medscape Medical News, the smoking cessation drug varenicline (Chantix) appears to…
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Carfentanil, an opioid said to be 100 times more powerful than fentanyl, has been tied to at least 700 deaths in numerous states. Worst hit include Michigan, Florida, and Ohio,…
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The number of retirement-age Americans taking at least three psychiatric drugs more than doubled between 2004 and 2013, even though almost half of them had no mental health diagnosis on…
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The latest edition of Psychopharmacology Bulletin is now available at: https://medworksmedia.com/product-category/psychopharmacology-bulletin/psychopharmacology-47-no-1/. Manuscripts include: Asenapine for the Control of Physical Aggression: A Prospective Naturalist Pilot Study By Jin Shi Amon, Sarah B. Johnson,…
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In a surprise to the conservative treatments by neurologists, tailored exercise treatment programs are being developed by physical therapists to specifically counter the unique movement impairments associated with Parkinson’s by…
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Deep brain stimulation, an established therapy that modifies the brain's circuitry to treat symptoms of depression, Parkinson's disease and other movement disorders, is attracting fresh attention from medical-device makers who…
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Charles Marmar, a 71-year-old psychiatrist in New York, has spent his career studying post traumatic stress disorder, which has symptoms such as sleep disruption and vivid flashbacks of the traumatic…
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Although past research has shown a link between renal dysfunction and cognitive impairment, a new systematic review shows that the presence of albuminuria specifically is also associated with an increased…
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Seven years after safety concerns altered the trajectory of Pfizer’s stop-smoking med Chantix, the FDA has pulled its black-box warning from the drug’s label, according to a well known online…
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Trends in Marijuana Use Among Pregnant and Nonpregnant Reproductive-Aged Women, 2002-2014 Qiana L. Brown, Aaron L. Sarvet, Dvora Shmulewitz Methods The Columbia University Medical Center institutional review board waived review of this study. Informed oral…
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Researchers have identified six regions of the human genome that are significantly linked to personality traits, and some show significant correlations to certain psychiatric disorders as well. The study, conducted…
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Psychiatrist Anna Lembke, chief of addiction medicine at Stanford University’s medical school, has spent her career helping patients battle their addiction to opioid drugs, from Vicodin to heroin. Out of…
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Every breath we take, especially the slow, deep breathing used in meditation, stimulates the vagus nerve to calm the body. Scientists also believe stimulating the nerve with small electrical impulses…
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Promising research into PTSD and the psychological effects of cancer such as anxiety and depression, have cast new light on the party drug, ecstasy (MDMA), and a hallucinogenic ingredient in "Magic…
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While the debate rages whether the drug epidemic in the United States is best served by walls or treatment, millions of Americans suffer from alcoholism or addiction to legal and…
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For centuries yogis have used breath control, or pranayama, to promote concentration and improve vitality. Buddha advocated breath-meditation as a way to reach enlightenment. Science is just beginning to provide…
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Giving severely depressed patients the arthritis drug celecoxib (brand name Celebrex) dramatically boosted the effectiveness of their antidepressant medication, according to new research. Patients were randomly assigned to receive the…
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A recent review of clinical evidence published in Mayo Clinic Proceedings by National Institutes of Health (NIH) researchers suggests that complementary health techniques have a legitimate place in a physician’s pain…
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Cambridge researchers believe Facebook status updates, “likes” and even photos, could help professionals better understand mental health disorders. Investigators believe that with the right ethical safeguards, social networks may even…
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New research offers a glimpse into the addicted brain, finding that the drugs appear to blunt a person’s natural parenting instincts. Researchers at the Perelman School of Medicine at the University…
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psychopharmacology-bulletin-36-articles-uploaded-to-pubmed October 13, 2016. Los Angeles CA Contact: James La Rossa Jr., or Michael E. Thase, MD, at 310.374.1300 www.medworksmedia.com Psychopharmacology Bulletin 36 Articles Uploaded to PubMed Replica Journal…
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By James Knickman, PhD, Ranga Krishnan, MB, ChB, and Harold Pincus, MD The United States needs to do more to help improve the outcomes of people with mental health disorders, substance use disorders, or both. In 2014,…
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Original Investigation ABSTRACT Importance Despite recent increased use of antidepressants in the United States, concerns persist that many adults with depression do not receive treatment, whereas others receive treatments that…
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Older people tend to be happier than younger people, and their happiness increases with age, according to psychiatric researchers who studied 1,546 people aged 21 to 99. Though the older…
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By Evdokia Anagnostou, MD1; Michael G. Aman, PhD; Benjamin L. Handen, PhD, et al. ABSTRACT Importance Atypical antipsychotic medications are indicated for the treatment of irritability and agitation symptoms in…
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EDITORIAL By Christopher J. McDougle, MD In this issue of JAMA Psychiatry, Anagnostou et al1 present results of a double-blind, placebo-controlled study of metformin for weight management in children and…
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https://medworksmedia.com/product-category/psychopharmacology-bulletin/psychopharmacology-46-2/ For Immediate Release August 18, 2016. Los Angeles CA Contact: James La Rossa Jr., or Michael E. Thase, MD, at 310.374.1300 New Issue of Psychopharmacology Bulletin ORIGINAL RESEARCH An…
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My Father's generation so admired the men and women that served in World War II, that when the Korean War raised its ugly head years later, he and my uncle…
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BACKGROUND Dialectical Behavior Therapy (DBT) is a treatment that focuses on helping patients to better manage their emotions, and develop skills to cope with problems and negative feelings. A primary…
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Writing in the JULY/AUGUST 2016 ISSUE of The Atlantic, Moises Velasquez-Manoff describes a 13-year-old boy named Sasha who was admitted to a hospital with what could only be described as…
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Efficacy and Safety of Basimglurant as Adjunctive Therapy for Major Depression: A Randomized Clinical Trial Jorge A. Quiroz, MD, MBA; Paul Tamburri, PharmD; Dennis Deptula, PhD; Ludger Banken, PhD; Ulrich Beyer, PhD; Michael Rabbia, MA; Nikhat Parkar, MSc; Paulo Fontoura, MD, PhD; Luca Santarelli, MD ABSTRACT Importance Antagonism of…
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New York University’s medical school has quietly shut down eight studies at its prominent psychiatric research center and parted ways with a top researcher after discovering a series of violations…
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After major policy changes in the United States, policymakers, health care professionals, and the general public seek information about whether recreational cannabis use is associated with physical health problems…
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A Longitudinal Comparison of Persistent Cannabis vs Tobacco Users Marijuana users might glean some good news from a soon to be published report comparing Cannabis vs. tobacco users, except when…
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Medworks Media - 2016 MEDWORKS MEDIA June 3, 2016 Los Angeles CA www.medworksmedia.com Psychopharmacology Bulletin DIGITAL ISSN: 2472-2448; PRINT ISSN: 0048-5764 Call For Papers — 2016/2017 New Section…
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By Natalie Parletta, Theophile Niyonsenga, and Jacques Duff Abstract Background There is evidence that children with Attention Deficit Hyperactivity Disorder (ADHD) and Autistic Spectrum Disorder (ASD) have lower omega-3 polyunsaturated fatty acid…
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By Arthur Caye; Thiago Botter-Maio Rocha, MD, MSc; Luciana Anselmi, PhD; Joseph Murray, PhD; Ana M. B. Menezes, PhD; Fernando C. Barros, PhD; Helen Gonçalves, PhD; Fernando Wehrmeister, PhD; Christina M. Jensen, MSc; Hans-Christoph Steinhausen, MD, PhD, DMSc; James M. Swanson, PhD; Christian Kieling, MD, PhD; Luis Augusto Rohde, MD, PhD ABSTRACT Importance The requirement…
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I am a third-generation New Yorker. Until I moved to the minicity of Manhattan Beach, CA., in the south bay of Los Angeles, the only other place I called home…
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By Julie A. Jacob, MA Try nonpharmacologic and nonopioid therapies first, the Centers for Disease Control and Prevention (CDC) recommended in a recently published opioid prescribing guideline for primary care clinicians in outpatient…
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May 17, 2016. Los Angeles, CA. My head still throbbing this morning from last night’s late arrival from Atlanta, I sought solace in the quietude of the Science Section of…
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Pharmaceutical heavyweight, Shire, best known in the US for its ADHD medications, presented new research on Binge Eating Disorder (B.E.D.) and Attention-Deficit/Hyperactivity Disorder (ADHD) at the American Psychiatric Association (APA) in…
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Monday, May 16, 2016. APA Meeting, Atlanta, GA. #APAAM16 For both men and women being married is associated with significantly reduced risk for alcohol use disorder compared to unmarried individuals.…
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By Domenico Giacco and Stefan Priebe Abstract Background Psychiatric patients showing risk to themselves or others can be involuntarily hospitalised. No data is available on whether following hospitalisation there is a…
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Sunday, May 15, 2016. APA Meeting, Atlanta GA. Charles B. Nemeroff, MD, PhD, the Leonard M. Miller Professor & Chairman, Department of Psychiatry and Behavioral Sciences and Director, Center on Aging…
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Sunday, May 15, 2016. APA Meeting, Atlanta GA. Nearly two-thirds of Americans say untreated mental illness has a significant negative impact on the U.S. economy and more than 75 percent…
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A UK Population-Based Electronic Health Records Study Joseph F. Hayes, MSc, MBChB; Alexandra Pitman, PhD; Louise Marston, PhD; Kate Walters, PhD; John R. Geddes, MD; Michael King, PhD; David P. J. Osborn, PhD (JAMA Psychiatry. Published online May 11, 2016. doi:10.1001/jamapsychiatry.2016.0432) ABSTRACT Importance Self-harm…
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Saturday, May 14, 2016. APA Meeting, Atlanta GA. The American Psychiatric Association (APA) convocation, which began today, highlighted initial findings in a number of key and unique mental diseases. Adopting…
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Saturday, May 14, 2016. APA Meeting, Atlanta GA. The American Psychiatric Association (APA) released the third edition of the Practice Guidelines for the Psychiatric Evaluation of Adults. While this latest…
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Is Special K the Anti-Depressant We’ve Waited For? A groundbreaking study on the popular club drug shows its massive potential in treating depression, with a ketamine spray coming to market…
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Pfizer ($PFE) has been trying to get the FDA to take the black box warning off its smoking cessation drug, Chantix, after regulators warned that the med could be linked…
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Citing Stigma of Mental Illness, Weil Family Donates $185 Million for Neuroscience Center at U.C.S.F
The philanthropists, Sanford I. Weill and his wife, Joan, have made the largest donation in the University of California, San Francisco's (UCSF) history, to finance a neuroscience center to provide…
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CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016 Deborah Dowell, MD, MPH; Tamara M. Haegerich, PhD; Roger Chou, MD ABSTRACT Importance Primary care clinicians find managing chronic pain challenging. Evidence of long-term efficacy of…
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For Immediate Release April 13, 2016. Los Angeles CA www.medworksmedia.com Psychopharmacology Bulletin Volume 46, Number 1, 2016, On-Line Now Replica Journal Issue Available for Readers ORIGINAL RESEARCH A…
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By GRETCHEN REYNOLDSThe New York Times Magazine4.10.16 More people are living longer these days, but the good news comes shadowed by the possible increase in cases of age-related mental decline. By…
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By Trisha Suppes, M.D., Ph.D., Robert Silva, Ph.D., Josephine Cucchiaro, Ph.D., Yongcai Mao, Ph.D.,Steven Targum, M.D., Caroline Streicher, B.A., Andrei Pikalov, M.D., Ph.D., Antony Loebel, M.D. Abstract Objective: Accumulating evidence…
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Medicine is full of young recruits writing veterans’ books, war stories full of hopes and fears for the next in line. As in the military, a couple of years’ service…
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The American Foundation for suicide prevention has announced a series of 12 short, informative videos on suicide prevention, which feature AFSP-funded researchers who participated in the prestigious International Summit on…
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ABSTRACT Prenatal exposure to acetaminophen may result in compromised neurodevelopment through inflammatory and immunologic mechanisms, through predisposition to oxidative stress, and through endocrine, endogenous cannabinoid, and other mechanisms. Several small…
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For anyone who has had the great pleasure of reading Siddhartha Mukherjee's 2011 Pulitzer Prize winning "The Emperor of All Maladies: A Biography of Cancer," expect something very special when…
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A prominent Stanford neuroscientist and psychiatrist, and his colleagues gives some clues about what makes some people risk-averse and others risk-taking. Answers could have implications for how to treat, curb…
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In a recent study, researchers looked at the possibility of using nutritional intervention to slow the onset of certain Alzheimer’s symptoms. The study involved a particular nutritional drink called Souvenaid…
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The New York Times will report tomorrow that an experimental drug derived from marijuana has succeeded in reducing epileptic seizures in its first major clinical trial, the product’s developer announced…
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For Immediate Release March 7, 2016. Los Angeles CA Contact: James La Rossa Jr., 310.374.1300 2016 Issues, Set for Index Medicus, are In Press Psychopharmacology Bulletin — reactivated by the…
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Antipsychotic Management of Schizoaffective Disorder: A Review Jean-Pierre Lindenmayer, and Amandeep Kaur The Cost Effectiveness of Limsdexamafetamtine Dimesylate for the Treatment of Binge Eating Disorder in the USA Tama ́sA ́gh
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In the summer of 1997, I was months away from launching the first consumer magazine about mental illness. My company had acquired a state and federal trademark for the title,…
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Other than the obvious onset of the mental disorder itself, postpartum depression is one of those illnesses that is hard to predict, and according to published records, may be even…
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Proton Pump Inhibitor's (or P.P.I.s), widely available by prescription or over the counter brands like Prevacid, Nexium, and Prilosec, have been tied to Alzheimer's Disease and other dementias, according to…
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By Tyler Nix, Kathryn Funk, Jeffrey S. Reznick, and Erin Zellers A wealth of medical history awaits your exploration in the National Library of Medicine’s (NLM) free and full-text digital…
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Michael E. Thase, Charles B. Nemeroff and Philip T. Ninan round out the group.
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A recent study published in Biological Psychiatry brings scientific thoroughness to mindfulness meditation and for the first time shows that, unlike a placebo, it can change the brains of ordinary people and…
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Last week, CNN published a piece about the tech industry's secret struggle with suicide and mental illness, relaying several stories of silent sufferers whose endings were tragic. And, unfortunately, suffering…
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A combination of aerobic exercise and focused-attention meditation performed twice weekly significantly improves symptoms of major depressive disorder (MDD) after just 8 weeks, new research shows. " combining these two…
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The US Preventive Services Task Force Recommendation on Screening for Autism Spectrum Disorder Michael Silverstein, MD, MPH; Jenny Radesky, MD In this issue of JAMA, the US Preventive Services Task Force (USPSTF) presents final…
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A new study shows that people with sleep apnea show significant changes in the levels of two important brain chemicals. This could be the reason so many people with sleep…
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In a study published Wednesday in The New England Journal of Medicine, Authors provide the strongest evidence to date that a more educated population and better cardiovascular health are contributing…
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Latest Psychiatric News: Menopause & Depression, World Mental Health Surveys, and Early Intervention
Early Intervention for Psychotic Disorders: Building Population Health Systems This Viewpoint proposes a conceptual framework for population health systems that would enable early intervention services for patients with new-onset psychotic disorders.…
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By Catherine Lombard, Cheryce Harrison, Samantha Kozica, Sophia Zoungas, Sanjeeva Ranasinha, and Helena Teede Abstract Background Obesity is reaching epidemic proportions in both developed and developing countries. Even modest weight gain increases the risk for…
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By Alexander C. Tsai, Mark Tomlinson, W. Scott Comulada, and Mary Jane Rotheram-Borus Abstract Background Violence against women by intimate partners remains unacceptably common worldwide. The evidence base for the assumed psychological…
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Let’s face it. We live in the age of technology. Things that were learned through books, lectures, and hand-written practices when we were kids are now being learned through games,…
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From The New York Times, Thursday, January 28. Scientists reported on Wednesday that they had taken a significant step toward understanding the cause of schizophrenia, in a landmark study that…
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Screening of Pregnant Women and New Mothers a Priority January 26, 2016. CNN reports this morning that if new recommendations by the U.S. Preventive Services Task Force are followed, primary care…
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According to Richard A. Friedman, a professor of clinical psychiatry and the director of the psychopharmacology clinic at the Weill Cornell Medical College, writing in Sunday's New York Times, "Who among us hasn’t…
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Abstract Many studies indicate a crucial role for the vitamin B12 and folate-dependent enzyme methionine synthase (MS) in brain development and function, but vitamin B12 status in the brain across…
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Federal prosecutors in Philadelphia said on Wednesday that they had indicted five people, including two research scientists, on charges of stealing trade secrets about drugs to treat cancer and other…
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Editorial | January 20, 2016 Sharing Clinical Trial Data: A Proposal From the International Committee of Medical Journal Editors The International Committee of Medical Journal Editors (ICMJE) believes that there is…
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Serotonin Improves High Fat Diet Induced Obesity in Mice Animal studies are not the usual coverage topic of brainscienceblogs.com. However, in this instance, we could not resist. Serotonin (5-HT) is…
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NEW YORK, Jan. 13, 2016 /PRNewswire/ -- Today, The Jed Foundation (JED) and the Steve Fund, two leading mental health organizations, announced a joint plan to provide colleges and universities…
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In a clear signal that medicine and politics make strange bedfellows, a crucial Senate committee on Tuesday, which unanimously approved Dr. Robert M. Califf, a cardiologist and clinical trial expert from…
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SILVER SPRING, Md. — A panel of medical experts recommended Tuesday that the Food and Drug Administration approve a new way of treating opioid addicts, using a slender rod implanted…
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The biggest winners--and losers--in the 2015 race for new drug approvals Let's start with the good news. In 2015, the FDA by its own account approved 45 new drugs, the…
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Role of the FDA in Affordability of Off-Patent Pharmaceuticals Jeremy A. Greene, MD, PhD; Gerard Anderson, PhD; Joshua M. Sharfstein, MD In recent weeks, the increasing prices of off-patent pharmaceuticals have been the subject of…
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For Immediate Release December 31, 2015. Los Angeles CA Contact: James La Rossa Jr., 310.374.1300 MedWorks Media Inc., established in 1994 as one of the largest publishers of journals and…
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Pharmacologic Therapy for Post Traumatic Stress Disorder: Review of Prescriptions and Potential Drug-Drug Interactions in a Military Cohort Kara L. Jablonski, PharmD, BCPS; Maria D. Devore, MS; Margaret A. Ryan,…
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What Will Health Care Look like in 20-Years? The Microbiome: Beyond the Gut The Microbiome/Inflammation/Infection Link The Microbiome/Environment Link Genomics: The Revolution We've All Been Waiting For Pharmacogenomics Medicine Goes…
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At the American College of Rheumatology (ACR) annual meeting, a neurologist and a rheumatologist took the stage to debate whether or not opioid analgesic medications belong in the management of…
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The results of this meta-analysis demonstrate that serum IGF-1 levels were significantly higher in de novo, drug-naïve PD patients compared with healthy controls. Nevertheless, additional endeavors are required to further…
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PHILADELPHIA — New open-label data from the expanded-access treatment program involving the cannabidiol Epidiolex (GW Pharma) show the median reduction in frequency of convulsive seizures after 3 months of treatment…
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The US Food and Drug Administration (FDA) has approved a chewable tablet form of extended-release methylphenidate (QuilliChew ER, Pfizer Inc) for attention-deficit/hyperactivity disorder (ADHD) in children aged 6 years and…
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HUNTINGTON BEACH, California ― Results of a large, multicenter, randomized trial show that extended-release (ER) naltrexone (Vivitrol, Alkermes, Inc) can effectively prevent opioid relapse among a particularly vulnerable population: adults…
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What is this new insanity drug of abuse known as gravel or flakka? Recent news reports detail a man, who thought he was being chased by dozens of cars, using…
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Rexulti: New treatment for schizophrenia and major depressive disorder approved and released by FDA On July 10, the U.S. Food and Drug Administration approved Rexulti (brexpiprazole) tablets to treat adults…
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Repetitive training, used widely in autism education, may hinder the learning process by promoting inflexibility, a new study with potentially "earthshaking" implications shows. The study unexpectedly found that repetitive training,…
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The Centers for Disease Control and Prevention (CDC) has issued a warning regarding increases in fentanyl drug confiscations and a potential increased risk for fentanyl-related overdose fatalities. According to the…
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CHICAGO — Taking a probiotic strain of Bifidobacterium longumreduced physiologic and psychological stress and led to a modest improvement in memory in a small pilot study of healthy men. The…
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The US Food and Drug Administration (FDA) has approved an injectable, long-acting version of Alkermes Inc's atypical antipsychotic aripiprazole to treat adults with schizophrenia. Aripiprazole lauroxil (Aristada) is administered every…
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The US Food and Drug Administration (FDA) has approved the amphetamine Dyanavel XR (Tris Pharma Inc), a once-daily extended-release oral liquid, for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children…
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RESEARCH ARTICLE Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study Yasmina Molero1, Paul Lichtenstein2, Johan Zetterqvist2, Clara Hellner Gumpert1, Seena Fazel3* 1 Center for Psychiatry Research, Department of…
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The Efficacy and Tolerability of Once-daily Controlled-release Trazodone for Depressed Mood, Anxiety, Insomnia, and Suicidality in Major Depressive Disorder By David V. Sheehan, MD, MBA; Anna Rozova, MSc, MD; E.…
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Psychopharmacology BULLETIN Newsletter the advance newsletter of Psychopharmacology BULLETIN Summary—Index of This Issue On-Press ORIGINAL RESEARCH EVIDENCE-BASED MEDICINEORIGINAL RESEARCH: The Trials and Travails Atypical Antipsychotic Drugs and Diabetes in the…
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• ORIGINAL RESEARCH • EVIDENCE BASED MEDICINE • GENERAL PSYCHIATRY Seroquel Once a Day: A Randomized, Double-Blind, Placebo-Controlled Study— This 6-week, randomized, double-blind study aimed to demonstrate efficacy of once-daily…
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Newsletter No. 3, 2008 www.psychopharmbulletin.com Volume 41 • Number 3 • 2008 Psychopharmacology BULLETIN Newsletter the advance newsletter of Psychopharmacology BULLETIN Summary—Index of This Issue On-Press ORIGINAL RESEARCH EVIDENCE…
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Newsletter No. 2, 2008 www.psychopharmbulletin.com Volume 41 • Number 2 • 2008 Psychopharmacology BULLETIN Newsletter the advance newsletter of Psychopharmacology BULLETIN Summary—Index of This Issue On-Press • ORIGINAL…
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• ORIGINAL RESEARCH • EVIDENCE BASED MEDICINE ORIGINAL RESEARCH: The Trials and Travails Placebo-Controlled — PTSD Double-Blind — ADHD Pilot-Controlled — GAD Comparative Analysis — ANTIDEPRESSANT TRIALS A Placebo-Controlled Trial…
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Psychiatry in the Postgenomic Era Kathy L. Kopnisky, PhD Steven E. Hyman, MD Dr. Kopnisky is assistant to the director, and Dr. Hyman is director, both at the National Institute…
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Pharmacogenomics of Antidepressants: Drug Discovery, Treatment, and Ethical Considerations Julio Licinio, MD Jonas Hannestad, MD, PhD Ma-Li Wong, MD Dr. Licinio is professor of psychiatry and biobehavioral sciences and medicine/endocrinology…
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THE ADVANCE NEWSLETTER OF PSYCHOPHARMACOLOGY BULLETIN Summary—Index of This Issue On-Press Newsletter No. 4, 2007 www.psychopharmbulletin.com Volume 40 • Number 3 • 2007 This newsletter is a synopsis of topical…
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THE ADVANCE NEWSLETTER OF PSYCHOPHARMACOLOGY BULLETIN Summary—Index of This Issue On-Press Newsletter No. 5, 2007 www.psychopharmbulletin.com Volume 40 • Number 3 • 2007 This newsletter is a synopsis of topical…
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Functional images of the brain and psychopharmacology Dr. Humberto Nicolini The various techniques of functional brain imaging have evolved surprisingly Ulti-mos in 15 years. Since the appearance of the skull…
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Abstracts of the XII World Congress of Psychiatry of the World Association of Psychiatry in Yokohama, Japan Chosen by Drs. John E. Mezzich and Miguel R. Jorge Profile of…
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Abstracts of XVII Peruvian Congress of Psychiatry "Federico Sal y Rosas" Bolivarian II Regional Meeting of the Latin American Psychiatric Association and I Regional Meeting of the World Psychiatric Association…
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Summaries from the World Congress of Sexology held in Havana, Cuba, from 10 to 14 March Chosen by Dr. Carlos Berganza The role of hotlines in clinical sexology: the…
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Keywords: bipolar disorder, drug treatment, mood disorders, mania, schizophrenia, depression mayorLineamientos consensus of experts for the pharmacological treatment of bipolar disorder: a new therapeutic tool Dr. David A. Kahn, Dr.…
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Therapeutic and diagnostic ADHD Guide - Part I Dr. Peter S. Jensen and Ms. Maura Crowe Background disorder attention deficit hyperactivity disorder (ADHD) is the most common behavioral /…
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Delirium Trihexyphenidyl Hydrochloride Dr. Andres and Dr. Jaime Solis Heerlein Summary For a patient of 17 years old, single, student, who is taken by her parents to consult the…
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Light therapy for seasonal depressive disorder Dr. Andrés Heerlein Introduction Since the work of Rosenthal and colleagues1 pioneers of seasonal affective disorder (SAD) and phototherapy, many authors have stressed…
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2007 Edition, N. 3 MEDWORKS Vol. 40 - No. 2 - 2007 ------------------------------------------------------------------------ THE TRIALS AND TRIBULATIONS OF ARIPIPRAZOLE The objective of the study was to assess the efficacy and…
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Publisher’s Statement New York: 9/11/01 A Personal Reckoning By James La Rossa Jr. There are two roadway approaches to New York City from which the awesome grandeur and sheer power…
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Pharmaceutical Complex Zyban Rising: Smokers Thwart Insurance Carriers But Get What They Pay for By James La Rossa Jr. While the latest smoking cessation therapy utilizing the compound Zyban is…
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Point & Commentary Physicians Back in the Driver’s Seat By James M. La Rossa Jr. At the beginning of 1997, the seasoned CBS newsman, Mike Wallace, and his wife Mary,…
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Guest Editorial A u t i s m : A Personal Insight B y T e m ple G r a n d i n , P h D W…
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EDITOR’S NOTE The Next Step Forward: A Move Toward Evidence, and Away From Fear of the Industry By Michael E. Thase, MD It is both an honor and a ch…
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2007 Edition, N. 2 ORIGINAL RESEARCH Vol. 39 No. 1 - Vol. 40, No. 1 ------------------------------------------------------------------------ IS ANTIDEPRESSANT SELECTION RATIONAL? Every clinician faces the daily question of which antidepressant is…
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2007 Edition, N. 1 ORIGINAL RESEARCH Vol. 39 No. 1 - Vol. 40, No. 1 ------------------------------------------------------------------------ DEBATING PSYCHOTROPICS AND SUICIDALITY Until now, it has been unclear if the suicide risk…
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A Long-Revered Resource in Academia Published from 1965 until 2000 by the National Institute of Mental Health (NIMH), Psychopharmacology BULLETIN forged its path just as psychiatry itself was embarking on…
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