Divalproex in the Treatment of Bipolar Disorder
By Paul E. Keck, Jr, MD, and Susan L. McElroy, MD
The Efficacy of Divalproex for Partial Epilepsies
By Michael C. Smith, MD
Divalproex and Epilepsy
By L. James Willmore, MD
Pharmacokinetics, Drug Interactions, and Tolerability of Valproate
By C. Lindsay DeVane, PharmD
Pharmacology of Valproate
By Michael J. Owens, PhD, and Charles B. Nemeroff, MD, PhD
The History of Valproate in Clinical Neuroscience
By Thomas R. Henry, MD
Efficacy and Tolerability of Controlled-Release Paroxetine
By Robert N. Golden, MD
Paroxetine Treatment of Mood and Anxiety Disorders in Children and Adolescents
By Karen Dineen Wagner, MD, PhD
Clinical Management of Perinatal Depression: Focus on Paroxetine
By D. Jeffrey Newport, MD, MSCR, MDiv, and Zachary N. Stowe, MD
Paroxetine Treatment of Mood Disorders in Women: Premenstrual Dysphoric Disorder and Hot Flashes
By Kimberly A. Yonkers, MD
Paroxetine Treatment of Depression in Late Life
By Charles F. Reynolds III, MD
Paroxetine Use in Medically Ill Patients
By Steven Stout, MD, PhD, Wendy I. Somerset, MD, Andrew Miller, MD, and Dominique L. Musselman, MD, MS
Advances in Recognition and Treatment of Social Anxiety Disorder: A 10-Year Retrospective
By Murray B. Stein, MD, FRCPC
Obsessive-Compulsive Disorder: Implications of the Efficacy of an SSRI, Paroxetine
By Philip T. Ninan, MD
Treatment of Posttraumatic Stress Disorder: The Impact of Paroxetine
By Jonathan R.T. Davidson, MD
Paroxetine Treatment of Generalized Anxiety Disorder
By David V. Sheehan, MD, MBA, and C. Gloria Mao, PharmD
Treatment of Panic Disorder: Focus on Paroxetine
By Mark H. Pollack, MD and Alicia C. Doyle, BA
Paroxetine Treatment of Major Depressive Disorder
By Martin B. Keller, MD
Pharmacokinetics, Drug Interactions, and Tolerability of Paroxetine and Paroxetine CR
In Vivo Neuroimaging Correlates of the Efficacy of Paroxetine in the Treatment of Mood and Anxiety Disorders
By Clinton Kilts, PhD
Neuropharmacology of Paroxetine
Advancing the Treatment of Mood and Anxiety Disorders: The First 10 Years’ Experience with Paroxetine
By Charles B. Nemeroff, MD, PhD
Management of Late-Life Depression: Focus on Comorbid Conditions
By Warren D. Taylor, MD, and K. Ranga Rama Krishnan, MB, ChB
Gender-Specific Differences in Depression and Treatment Response
By Susan G. Kornstein, MD, Diane M. E. Sloan, PharmD, and Michael E. Thase, MD
New Advances in the Management of Anxiety Disorders
By Mark H. Pollack, MD
Neurobiology and Mechanisms of Antidepressant Treatment Response in Anxiety
By Philip T. Ninan, MD, Sarah A. Feigon, PhD, and Bettina Knight, RN
Strategies for Treatment-Resistant Depression
By Christos Ballas, MD, Jeffrey P. Staab, MD, MS, and Dwight L. Evans, MD
Long-Term Antidepressant Treatment
By Katia K. Delrahim, BA, Rachel Maddux, BA, and Mark Hyman Rapaport, MD
Remission as the Critical Outcome of Depression Treatment
By Michael E. Thase, MD, Diane M. E. Sloan, PharmD, and Susan G. Kornstein, MD
New Developments in Depression and Anxiety Disorders
Raising the Expectations of Long-Term Treatment Strategies in Anxiety Disorders
Can We Distinguish Anxiety From Depression?
By David S. Baldwin, FRCPsych, Dwight L. Evans, MD, Robert M. A. Hirschfeld, MD, and Siegfried Kasper, MD
Unraveling the Diagnostic Clues of Depression and GAD: The Primary Care Challenge
By Johan A. den Boer, MD, Dwight L. Evans, MD, Sing Lee, MD, PhD, and Rafael Salin-Pascual, MD
Algorithms in Clinical Psychiatry: A Stepped Approach Toward the Path to Recovery
By Madhukar Trivedi, MD
Depression Treatment: A Lifelong Commitment?
By Martin B. Keller, MD, and Ernst R. Berndt, PhD
Mechanism of Action of Antidepressants
By Francesc Artigas, PhD, David J. Nutt, MD, PhD, and Richard Shelton, MD
Depression in the Elderly
By William M. McDonald, MD, Carl Salzman, MD, and Alan F. Schatzberg, MD
Coping With Somatic Comorbidities: Striving for Complete Recovery
By Christer Allgulander, MD, and Siegfried Kasper, MD
Optimizing Treatment Outcomes for Patients With Depression and Generalized Anxiety Disorder
By Michael E. Thase, MD, and Madhukar Trivedi, MD
Long-Term Treatment Strategies in Anxiety Disorders
By Christer Allgulander, MD, Robert M. A. Hirschfeld, MD, and David J. Nutt, MD, PhD
Generalized Anxiety Disorder: Raising the Expectations of Treatment
By Christer Allgulander, MD, and David V. Sheehan, MD, MBA
New Developments in the Neurobiological Basis of Anxiety Disorders
By Jack M. Gorman, MD, Robert M. A. Hirschfeld, MD, and Philip T. Ninan, MD
Long-Term Treatment Strategies in Affective Disorders
Recent Advances in the Neurobiology of Depression
Remission: Today’s Target in the Treatment of Mood and Anxiety Disorders
Comparing the Methods Used to Compare Antidepressants
By Michael E. Thase, MD
Intermittent Fluoxetine Dosing in the Treatment of Women With Premenstrual Dysphoria
By Meir Steiner, MD, PhD, FRCPC, Marilyn Korzekwa, MD, FRCPC, John Lamont, MD, MSc, FRCSC, and Annette Wilkins, BA
By Lindsay DeVane, PharmD
A Discussion on the Methodologies Used to Evaluate Antidepressants
MODERATOR: Jan A. Fawcett, MD
DISCUSSANTS: Norman Sussman, MD Jeffrey H. Newcorn, MD
Risperidone: Review of Its Therapeutic Utility in Depression
By Joyce E. Myers, MD, and Michael E. Thase, MD
A Model to Explain the Therapeutic Effects of Serotonin Reuptake Inhibitors: The Role of 5-HT2 Receptors
By Mikael Landén, MD, PhD, and Michael E. Thase, MD