Surgical Staging for Endometrial Cancer
By James W. Orr, Jr, MD, Phillip Y. Roland, MD, Pamela J. Orr, RN, OCN, and Dara D. Leichter, RN, OCN
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Treatment and Management of Cancer in the Frail Elderly
By Zeba S. Geloo, MD, and William B. Ershler, MD
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Palliative Care Options for Advanced Prostate Cancer
By Amir V. Kaisary, MA, ChM, FRCS, and Ross Knight, MRCS
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Letter From the Editors
Right Tool, Right Time, Right Reason
By J. Lyle Bootman, PhD, and Daniel D. Von Hoff, MD, FACP
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Use of Colony-Stimulating Factors in the Elderly Cancer Patient
By Gary H. Lyman, MD, MPH, FRCP (Edin), Lodovico Balducci, MD, and Yemi Agboola, MS
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Cancer Mortality in the Elderly, 1960–1998: A Worldwide Approach
By Carlo La Vecchia, MD, Franca Lucchini, BSc, Eva Negri,ScD, and Fabio Levi, MD
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Metastasis of an Esophageal Carcinoma to the Soft Tissue in the Elbow
By Arun Kumar, MD, Rajeev Kulkarni, MD, Emmanuel C. Besa, MD, and Carolyn E. Grotkowski, MD
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Assessing the Older Cancer Patient
By Martine Extermann, MD, PhD
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Pharmacy Practice
The Controversial Association of the Treatment of Infertility With Fertility Agents and Development of Ovarian Cancer:
What Should Patients Be Told?
By Judith A. Smith, PharmD, BCOP
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Pharmacology of Antineoplastic Agents in Older Cancer Patients
By J. Andrew Skirvin, PharmD, Sunitha Vemulapalli, MD, and Stuart M. Lichtman, MD
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The Case for Geriatric Oncology
By Lodovico Balducci, MD
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Letter From the Editors
A Standing Ovation for a Change in How We Treat Patients With Cancer —Forever
By Daniel D. Von Hoff, MD, FACP, and J. Lyle Bootman PhD
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Managing Deep Vein Thrombosis Risk in Oncology Patients Office and Outpatient Settings
MODERATOR: Brian A. Meltzer, MD, MBA
DISCUSSANTS: Leo R. Zacharski, MS, MD, and Steven R. Deitcher, MD
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Chemotherapy for Epithelial Ovarian Cancer
By Maurie Markman, MD
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Diagnosis and Staging of Gynecological Malignancies
By Brigitte E. Miller, MD
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The Role of Irradiation in Endometrial Cancer
By Perry W. Grigsby, MD
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Surgical Management of Epithelial Ovarian Cancer
By George Coukos, MD, PhD, and Stephen C. Rubin, MD
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Surveying the Field of Gynecologic Oncology
By William J. Hoskins, MD
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Letter From the Editors
Addressing the Quality Chasm for a New Health System in the 21st Century
By J. Lyle Bootman, PhD, and Daniel D. Von Hoff, MD
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Palliative Chemotherapy for Advanced Colorectal Cancer
By Peter Simmonds, FRACP, and Tim Iveson, MD
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Our Current Understanding of Genetic Alterations in Colorectal Cancer, and Implications for Clinical Use
By Manel Esteller, MD, PhD, and Montserrat Sanchez-Cespedes, PhD
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Flavonoids Join the War on Cancer
By Uwe Wenzel, PhD
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Pharmacy Practice
Oral Chemotherapy for Colorectal Cancer: An Update
By Sunil Sharma, MD
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Pharmacy Practice
In Vitro Tests to Predict Human Tumor Sensitivity to Cytotoxic Agents
By Axel-R. Hanauske, MD, PhD
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Pharmacy Practice
An Update on Cancer Chemoprevention
By Tammy Chernin, RPh
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Letter From the Editors: A Question of Ownership
By Daniel D. Von Hoff, MD, and J. Lyle Bootman, PhD
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Critical Analysis of Recent Phase III Studies for the Treatment of Colorectal Cancer Implications for Future Clinical Trial Design
DISCUSSANTS: John S. Macdonald, MD, Richard Goldberg MD, Leonard B. Saltz, MD, Daniel G. Haller, MD,
and Richard Simon, DSc
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Metastasis-Suppressor Genes: A Review and Perspective on an Emerging Field
By Barbara A. Yoshida, Mitchell M. Sokoloff, Danny R. Welch, and Carrie W. Rinker-Schaeffer
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Sequential Chemotherapy for the Curative Treatment of Squamous Cell Cancer of the Head and Neck: A New Paradigm
By Marshall R. Posner, MD
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Pharmacy Practice
Monitoring Chemotherapy in an Aging Population
By Judith A. Smith, Pharm.D, BCOP
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Breast Imaging: Economic Issues and Challenges
By Dione M. Farria, MD, MPH, and Stephen A. Feig, MD
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A Systematic Approach to Improving Care for Cancer Patients: Focus on Growth Factor Use and Outcomes
By Kimberly A. Bergstrom, PharmD, and Eric T. Herfindal, PharmD, MPH
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Letter From the Editors
Are We Prepared for the Genomics Era?
By J. Lyle Bootma
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The Genetics of Multiple Myeloma
By Brian Van Ness, PhD
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Diagnosis and Treatment of Depression in the Cancer Patient
Tracy L. Skaer, PharmD, Linda M. Robison, MSPH, David A. Sclar, PhD
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High-Dose Therapy in Patients with Multiple Myeloma
By Bhawna Sirohi, MBBS, DCH and Ray Powles, MD, MRCP, MRCPath
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Pharmacology and Therapeutic Use of Trastuzumab in Breast Cancer
By Imad Treish, PharmD, Rowena Schwartz, PharmD, BCOP, and Celeste Lindley, PharmD, BCPS, FASHP, FCCP
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Guest Editor
Research Needs in Myeloma
Gregory R. Mundy, MD
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Colorectal Cancer Screening: How Are We Doing and How Can We Improve?
Virender K. Sharma, MD, and Colin W. Howden, MD
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Increased Mortality Risk Associated With Medial Breast Tumors May Be Due to Untreated Internal Mammary Node Metastases
Caroline Lohrisch, MD