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Psychopharmacology Bulletin › All Volumes & Issues › VOL 43 No. 4 › Lamotrigine Adjunctive Therapy...
ORIGINAL RESEARCH

Lamotrigine Adjunctive Therapy to Lithium and Divalproex in Depressed Patients with Rapid Cycling Bipolar Disorder and a Recent Substance Use Disorder: A 12-week, Double-Blind, Placebo-Controlled Pilot Study

Zuowei Wang, Keming Gao, David E. Kemp, Philip K. Chan, Mary Beth Serrano, Carla Conroy, Yiru Fang, Stephen J. Ganocy, Robert L. Findling, Joseph R. Calabrese
Psychopharmacology Bulletin 43(4): 5-21, 2011/01/07; https://doi.org/10.64719/pb.4303

Abstract

Objective: To pilot the efficacy and safety data of lamotrigine adjunctive therapy to lithium and divalproex in patients with rapid-cycling bipolar disorder (RCBD) and a recent substance use disorder (SUD). Method: Structured Clinical Interviews were used to ascertain DSM-IV diagnosis of RCBD, SUDs, and other Axis I disorders. Patients who did not meet the criteria for a bimodal response after up

Keywords

bipolar disorder, lamotrigine, mood stabilizer, placebo-controlled trial, substance use disorder, treatment-refractory

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How to Cite

Zuowei Wang, Keming Gao, David E. Kemp, Philip K. Chan, Mary Beth Serrano, Carla Conroy, Yiru Fang, Stephen J. Ganocy, Robert L. Findling, Joseph R. Calabrese. Lamotrigine Adjunctive Therapy to Lithium and Divalproex in Depressed Patients with Rapid Cycling Bipolar Disorder and a Recent Substance Use Disorder: A 12-week, Double-Blind, Placebo-Controlled Pilot Study. Psychopharmacology Bulletin. 2011/01/07; 43(4):5-21. https://doi.org/10.64719/pb.4303