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Psychopharmacology Bulletin › All Volumes & Issues › VOL 43 No. 4
PSYCHOPHARMACOLOGY BULLETIN

VOL 43 No. 4

Articles in This Issue

ORIGINAL RESEARCH

Lamotrigine Adjunctive Therapy to Lithium and Divalproex in Depressed Patients with Rapid Cycling Bipolar Disorder and a Recent Substance Use Disorder: A 12-week, Double-Blind, Placebo-Controlled Pilot Study

Zuowei Wang, Keming Gao, David E. Kemp, Philip K. Chan, Mary Beth Serrano, Carla Conroy, Yiru Fang, Stephen J. Ganocy, Robert L. Findling, Joseph R. Calabrese
Objective: To pilot the efficacy and safety data of lamotrigine adjunctive therapy to lithium and divalproex in patients with rapid-cycling bipolar disorder (RCBD) and a recent substance use disorder (SUD). Method: Structured Clinical Interviews were...
Pages 5-21 Read Article
NEGATIVE AND FAILED CLINICAL TRIAL RESULTS

A Failed 6-Week, Randomized, Double-Blind, Placebo-Controlled Study of Once-Daily Extended Release Quetiapine Fumarate in Patients with Acute Schizophrenia: Lessons Learned

Andrew J. Cutler, Tram Tran-Johnson, Amir Kalali, Mikael Åström, Martin Brecher, Didier Meulien
To demonstrate the efficacy of once-daily extended release quetiapine fumarate (quetiapine XR) versus placebo in adults with acute exacerbation of schizophrenia. Methods: A 6-week, double-blind, randomized, placebo-controlled study. In- or out-patients with a DSM-IV diagnosis...
Pages 37-69 Read Article