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COMPLICATED CASE HISTORIES

Complete Resolution of Clozapine-Induced Sialorrhea with Low Dose Trihexyphenidyl

Samir Kumar Praharaj, Sujit Sarkhel, Roshan Vitthalrao Khanande, Vinod Kumar Sinha
Psychopharmacology Bulletin 43(4): 73-75, 2011/01/07; https://doi.org/10.64719/pb.4305

Abstract

Clozapine-induced sialorrhea (CIS) is a frequently occurring debilitating adverse effect. Although various treatment options exist, none has been proved to be distinctly superior to others. We report a case of CIS that responded to low dose of trihexyphenidyl (2 mg/day). Psychopharmacology Bulletin. 2010;43(4):73–75.

Keywords

clozapine, Hypersalivation, sialorrhea, Trihexyphenidyl

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How to Cite

Samir Kumar Praharaj, Sujit Sarkhel, Roshan Vitthalrao Khanande, Vinod Kumar Sinha. Complete Resolution of Clozapine-Induced Sialorrhea with Low Dose Trihexyphenidyl. Psychopharmacology Bulletin. 2011/01/07; 43(4):73-75. https://doi.org/10.64719/pb.4305