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Psychopharmacology Bulletin › All Volumes & Issues › VOL 46 No. 2 › Valproic Acid and...
COMPLICATED CASE HISTORIES

Valproic Acid and Hepatic Steatosis: A Possible Link? About a Case Report

Leila Mnif, Rim Sellami, Jawaher Masmoudi
Psychopharmacology Bulletin 46(2) :59-62 , 2016/08/15

Abstract

Background

Valproic acid is a mood-stabilizing anticonvulsant. Hepatic injuries are among the occasionally observed adverse effects of this medication.

Case presentation

We present the case of a 47-year-old man who had bipolar disorder for ten years and treated with valproic acid. He demonstrated elevated serum aminotransferases and ultrasonography revealed that hepatomegaly was suggestive of hepatic steatosis.

Conclusion

This case report stresses the importance of a complete drug history and the need for clinicians to be aware of the delayed onset of hepatic injuries.

Keywords

anticonvulsivant, bipolar disorder, hepatic steatosis, valproic acid

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How to Cite

Leila Mnif, Rim Sellami, Jawaher Masmoudi. Valproic Acid and Hepatic Steatosis: A Possible Link? About a Case Report. Psychopharmacology Bulletin. 2016/08/15; 46(2):59-62.