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Psychopharmacology Bulletin › All Volumes & Issues › VOL 46 No. 2
PSYCHOPHARMACOLOGY BULLETIN

VOL 46 No. 2

Articles in This Issue

ORIGINAL RESEARCH

An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder

Patricia Pilkinton, Carlos Berry, Seth Norrholm, Al Bartolucci, Badari Birur, Lori L. Davis
Objective Selective serotonin reuptake inhibitors (SSRIs) remain the first-line treatment for posttraumatic stress disorder (PTSD). However, adjunctive atypical antipsychotics are often used to target residual or refractory symptoms. Asenapine is a novel atypical antipsychotic that...
Pages 8-17 Read Article
EVIDENCE-BASED MEDICINE

Treatment of Autism Spectrum Disorder in Children and Adolescents

Melissa DeFilippis, Karen Dineen Wagner
Autism spectrum disorder is a diagnosis that includes significant social communication deficits/delays along with restricted patterns of interests and behaviors. The prevalence of this diagnosis has increased over the past few decades, and it is...
Pages 18-41 Read Article
DRUG DISPOSITION & PHARMACOKINETICS

Treatment Resistant Depression with Loss of Antidepressant Response: Rapid—Acting Antidepressant Action of Dextromethorphan, A Possible Treatment Bridging Molecule

Edward C. Lauterbach
Dextromethorphan (DM) may have ketamine—like rapid—acting, treatment—resistant, and conventional antidepressant effects. 1 , 2 This reports our initial experience with DM in unipolar Major Depressive Disorder (MDD). A patient with treatment—resistant MDD (failing adequate trials...
Pages 53-58 Read Article
GENERAL PSYCHIATRY

Maternal and Fetal Outcomes After Lamotrigine Use in Pregnancy: A Retrospective Analysis from an Urban Maternal Mental Health Centre in New Zealand

Chandni Prakash, Susan Hatters-Friedman, Charmian Moller-Olsen, Abigail North
Introduction Pregnancy is a vulnerable period for recurrence of bipolar disorder. Discontinuation of mood stabilisers during pregnancy and the postpartum period can significantly increase the risk of recurrence of bipolar disorder. Lamotrigine is an anti-epileptic...
Pages 63-69 Read Article