Abstract
Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioral condition in childhood that often persists into adulthood.1 Psychostimulant medication has demonstrated efficacy for managing ADHD symptoms in adults.2,3 • The development of formulations with varying durations of effect has greatly expanded the available treatment options for individuals with ADHD.4 Management of ADHD symptoms in adults may involve treatment with either short-acting (SA) medication, long-acting (LA) medication, or an adjunctive LA + SA (AU) medication regimen. These different formulation dosing regimens provide differing durations of effect and thus differing coverage of symptoms that can impair adult patients in their social, work, school, and/or family settings across the entire day (in early morning, late afternoon, and into the evening). • Few studies, however, have investigated how LA/SA formulations and differing formulation dosing regimens relate to differing medication coverage resulting in symptom impairments in adult patients with ADHD.5,6.
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