VOL 56 No. 2

Objective To provide an updated evaluation of the efficacy and safety of asenapine in bipolar disorder using evidence from randomized controlled trials. Methods An updated systematic review and pairwise meta-analysis was conducted in accordance with...

Objective To develop and validate a comprehensive questionnaire to assess academic stress, integrating academic anxiety and burnout. Method This study involved questionnaire development using existing instruments, namely DES, PSS, DASS-21, and MBI, and subsequent validation....

Background Suzetrigine is a novel non-opioid analgesic initially approved for acute pain management. There has been growing interest in its potential applications for chronic pain conditions. As clinical awareness and accessibility expand, evaluating early outpatient...

Background Tobacco use is a known contributor to poor health outcomes and may influence chronic pain severity and prognosis. Understanding smoking patterns among patients presenting to a chronic pain clinic provides valuable insight into patient...

Mood and anxiety disorders are leading causes of psychiatric hospitalization. However, data on real-world inpatient psychopharmacologic practices in the Philippines are limited. This study aims to describe the clinical characteristics and psychotropic medication prescribing patterns...

This randomized, controlled trial examined the safety of clavulanic acid (CLAV), a GLT-1 (astrocytic glutamate transporter) modulator, in combination with intravenous cocaine to determine whether CLAV can be safely studied in outpatients with cocaine use...

Body Dysmorphic Disorder (BDD) is an emerging mental health concern among young adults, particularly in urban settings where social media exposure intensifies appearance-related pressures. This study aimed to assess the prevalence of BDD among individuals...

Background Clozapine remains the most effective antipsychotic medication for treatment-resistant schizophrenia, but its use is limited by the risk of hematological side effects, particularly neutropenia. The present study aimed to determine the incidence and potential...

Purpose We aimed to synthesize and provide an updated meta-analysis of the current data on extended-release naltrexone (XR-NTX) and oral naltrexone (NTX) for alcohol use disorder (AUD). Methods A comprehensive database search was conducted and...

Fibromyalgia syndrome is a complex chronic pain syndrome associated with a broad constellation of symptoms, associated disorders, and possible risk factors. Although the pathophysiology of fibromyalgia remains unclear, there is promising research investigating neuroimaging, genetic...

Antipsychotics might be thought of as pleuripotent broad-spectrum psychotropics, given the versatile pharmacological portfolio, with a multitude of uses on clinical grounds, albeit off-label. Herein, authors would touch briefly on the general pharmacology and therapeutic...

~ Alzheimer’s disease (AD) is a devastating relentlessly progressive illness for which currently there is no definitive curative treatment. The mainstay of treatment remains symptomatic, though. Psychopharmacotherapy is only part of a multi-pronged package of...

Background Co-occurring substance use disorders and bipolar disorder present treatment challenges including poor medication adherence, increased relapse rates, and complex symptom interactions. This case series evaluates the feasibility and outcomes of concurrent long-acting injectable (LAI)...

Background Delusional misidentification syndromes are rare psychiatric conditions, and subjective double delusion is particularly uncommon in adolescents. Agomelatine, an antidepressant with melatonergic and serotonergic properties, has limited evidence in pediatric populations and may trigger mood...

We present a case of a 36-year-old female with schizophrenia, coronary artery disease, and type 2 diabetes who was hospitalized for altered mental status and persistent psychosis. Initial evaluation revealed myocardial infarction, pulmonary embolism, and...

We present the case of a young gentleman admitted to an inpatient psychiatric ward with a diagnosis of Bipolar Affective Disorder who developed Valproate-induced Hyperammonaemic Encephalopathy (VHE) alongside infection with COVID-19. His condition had exhibited...

Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by cognitive impairment, behavioral dysregulation, and emotional lability. While it is primarily known as a leading cause of inherited intellectual disability, patients with FXS may...

Objective To describe a rare case of non-catatonic mutism as the primary presentation of psychosis in a patient with complex comorbidities, highlighting diagnostic differentiation and antipsychotic response. Methods Case report of a 47-year-old female with...