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Psychopharmacology Bulletin › All Volumes & Issues › VOL 54 No. 4
PSYCHOPHARMACOLOGY BULLETIN

VOL 54 No. 4

Articles in This Issue

ORIGINAL RESEARCH

The Effectiveness and Safety of Stellate Ganglion Block in the Treatment of Symptoms from Long COVID-19: A Pilot Study

Alexa O Levey, Grant H Chen, Alexandra Ngyuen, Luis Ostrosky-Zeichner, Jamal Hasoon, Sepideh Saroukhani, Matthew Lin
Purpose Pilot study to evaluate the safety and effectiveness of stellate ganglion blocks in the treatment of symptoms related to long COVID infection. Materials and Methods A total of 17 patients who underwent stellate ganglion...
Pages 8-17 Read Article
ORIGINAL RESEARCH

Ultrasonically Determined Thyroid Volume in Individuals with Bipolar Disorder on Lithium Prophylaxis Compared with Healthy Controls

Anjali Bhasin, Devasenathipathy Kandasamy, Yashdeep Gupta, Raman Deep, Raka Jain
Introduction Lithium is a gold-standard agent for bipolar disorder (BD) and can affect the size, structure and/or function of thyroid gland with long-term exposure. Thyroid ultrasound can detect structural thyroid abnormalities, but it is under-reported...
Pages 18-34 Read Article
ORIGINAL RESEARCH

Metabolic Syndrome among Patients Taking Atypical Antipsychotics: A Comparative Cross-Sectional Study at Erada and Mental Health Complex in Taif, Saudi Arabia

Dhaifallah M Alhasani, Anas Ibn Auf, Ahmed A Alghamdi, Abdullah R Alzahrani
Introduction Second-Generation Antipsychotics (SGAs) are widely used for treating psychiatric disorders due to their favorable side effect profile compared to First-Generation Antipsychotics (FGAs). However, SGAs are associated with significant metabolic side effects. This study aims...
Pages 35-44 Read Article
GENERAL PSYCHIATRY

Serotonergic Drugs for the Treatment of Attention-Deficit/Hyperactivity Disorder: A Review of Past Development, Pitfalls and Failures, and a Look to the Future

Craig Chepke, Elizabeth Brunner, Andrew J Cutler
Serotonin has been implicated in the neurobiology of attention-deficit/hyperactivity disorder (ADHD) due to its association with impulsivity, attention, and emotional regulation. Many compounds with serotonergic properties have been evaluated in ADHD, but few have been...
Pages 45-80 Read Article
REVIEW ARTICLE

Intravenous Magnesium for the Management of Chronic Pain: An Updated Review of the Literature

Henry Onyeaka, Janet Adeola, Rebecca Xu, Adlai Liburne Pappy, Marchelle Smucker, Wisdom Ufondu, Moyasar Osman, Jamal Hasoon, Vwaire Orhurhu
Background Available therapeutic options are currently limited by their modest efficacy. As a result, novel pharmacotherapeutic treatments with different mechanisms have recently attracted empirical attention. Magnesium, a divalent cation, is postulated to provide analgesic and...
Pages 81-105 Read Article
REVIEW ARTICLE

Stellate Ganglion Blocks for Post-Traumatic Stress Disorder: A Review of Mechanisms, Efficacy, and Complications

Jamal Hasoon, Sana Sultana, Aila Malik, Patrick Brown, Alexa Ryder, Christopher L Robinson, Ivan Urits, Giustino Varrassi, Omar Viswanath
Post-traumatic stress disorder (PTSD) stands as a pervasive psychiatric condition, exerting a profound impact on millions across the globe. Despite the availability of traditional therapeutic modalities, many individuals continue to grapple with suboptimal treatment outcomes,...
Pages 106-118 Read Article
REVIEW ARTICLE

Psychopharmacotherapy of Pica- How Much Do We Know?

Ahmed Naguy, Nadyah Alayadhi, Soliman Al-Khadhari, Mohamed Y Abuzeid, Saxby Pridmore
There is little evidence for psychopharmacotherapy in pica. A few studies reported some benefit from the use of SSRIs, atypical antipsychotics and methylphenidate. That said, evidence to deploy these agents remains, at large, flimsy. Here,...
Pages 119-123 Read Article
COMPLICATED CASE HISTORY

Sublingual Atropine Administration for Clozapine-Induced Sialorrhea in Bipolar Disorder: A Case Report Highlighting its Efficacy, Safety Concerns and Challenges

Omar Afroz, Shaurya Garg, Amit Kumar, Preethy Kathiresan, Deepika Mishra, Raman Deep
We discuss a case with off-label sublingual administration of atropine for clozapine-induced sialorrhea (CIS) after failure of two commonly used agents to manage CIS. Atropine had a demonstrable efficacy, as measured by means of sialometry...
Pages 124-130 Read Article
CLINICAL PERSPECTIVE

Valproate-Autism Labyrinth

Ahmed Naguy, Maryam Alqabandi
Valproate and Autism complexity is manifold. From an established environmental risk factor for autism, to a translational animal model, valproate’s composite mode of action might unfold to address core autistic domains transcending mere aggressive behavioural...
Pages 131-133 Read Article