VOL 54 No. 1 Archives - MedWorks Media

ORIGINAL RESEARCH

A Phase 2 Open Label Study of Efficacy, Safety, and Tolerability of SLS-002 (Intranasal Racemic Ketamine) in Adults with MDD at Imminent Risk of Suicide

Timothy Whitaker, Kimberly F Farrand, Michael E Thase

Background Despite the prevalence of Major Depressive Disorder (MDD) and the propensity of affected individuals to eventually die by suicide, there is no therapeutic approved specifically for suicidal ideation and behavior (SI/B) in MDD. The...

Pages 8-17 Read Article

ORIGINAL RESEARCH

A Pilot Study to Explore the Effect of Long Acting Injectable Antipsychotics on Aggression

Tiffany M Hopkins, O. Greg Deardorff, Yifei Liu, Megan G Trout, Roger W Sommi, Niels C Beck

Objectives To explore the effect of switching from an oral antipsychotic to a long-acting injectable (LAI) antipsychotic on aggression, in terms of the changes of verbal and physical aggression, interventions required, self-injurious behavior, use of...

Pages 18-24 Read Article

GENERAL PSYCHIATRY

Duration of Untreated Illness in Obsessive-Compulsive Disorder and its Associated Factors

Anas Ibn Auf, Abdelgadir Osman

Introduction The period before effective treatment is administered, is known as the duration of untreated illness (DUI). It has been found to relate to prognoses and sensitivity to treatment. The DUI is yet to be...

Pages 25-32 Read Article

COMPLICATED CASE HISTORIES

New-Onset Prolonged Psychosis Following Synthetic Cannabinoid Use in an Older Patient: A Case Report

Ahmed Alhassan, Srihari R Prahad, Bradley G Burk, Rachel E Fargason, Badari Birur

Synthetic cannabinoids (SCs), a class of new psychoactive substances (NPS) commonly known as “spice,” has rapidly gained popularity and become the most ubiquitous NPS on the illegitimate drug market. SCs, unlike natural cannabis (NC), are...

Pages 33-39 Read Article

COMPLICATED CASE HISTORIES

Pregabalin Adjuventia Helped Risperidone-Induced Extrapyramidal Syndrome and Augmented Antipsychotic Response in an Adolescent with Schizophrenia

Ahmed Naguy, Saxby Pridmore, Bibi Alamiri

Here, authors report on an interesting case of early-onset of schizophrenia where adjunctive pregabalin alleviated risperidone-induced pseudoparkinsonism, helped with insomnia and agitation and boosted antipsychotic response with great tolerability. We wager that gabapentenoids can be...

Pages 40-42 Read Article

REVIEW ARTICLE

A Comprehensive Review of Lemborexant to Treat Insomnia

Mitchell C. Fuller, Samuel F. Carlson, Chris Grant, Vince Berry, Marko Ivancich, Elyse M. Cornett, Adam M. Kaye, Omar Viswanath, Ivan Urits, Sahar Shekoohi, Alan D. Kaye

Purpose of Review This is a comprehensive review of the literature regarding Lemborexant for the treatment of insomnia. It covers the background and management of insomnia and then reviews the body of existing evidence evaluating...

Pages 43-64 Read Article

REVIEW ARTICLE

A Comprehensive Review of Solriamfetol to Treat Excessive Daytime Sleepiness

Mitchell C. Fuller, Samuel Carlson, Haley Pysick, Vince Berry, Andrew Tondryk, Hayden Swartz, Elyse M. Cornett, Adam M. Kaye, Omar Viswanath, Ivan Urits, Alan D. Kaye

Purpose of Review This is a comprehensive review of the literature regarding the use of Solriamfetol for excessive daytime sleepiness. It covers the background and current therapeutic approaches to treating excessive daytime sleepiness, the management...

Pages 65-86 Read Article

VOL 54 No. 1

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