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Psychopharmacology Bulletin All Volumes & Issues VOL 52 No. 2
PSYCHOPHARMACOLOGY BULLETIN

VOL 52 No. 2

Articles in This Issue

ORIGINAL RESEARCH

Demographic and Clinical Characteristics of Antipsychotic Drug-Treated Older Adults with Bipolar Disorder from the Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE –BD)

Objectives Antipsychotic drugs (APS) are widely used to treat patients with bipolar disorder (BD), but there is limited information in older-age bipolar disorder (OABD). This analysis of the Global Aging & Geriatric Experiments in Bipolar...
REVIEW ARTICLE

Short Term Second-Generation Antidepressant Monotherapy in Acute Depressive Episodes of Bipolar II Disorder: A Systematic Review and Meta-Analysis

Purpose Bipolar II disorder (BD-II) has limited evidence-based treatment guidelines. The aim of this systematic review and meta-analysis was to estimate the efficacy and safety of second-generation antidepressant (SGAD) monotherapy in acute BD-II depression. Methods...
REVIEW ARTICLE

The Prescriber’s Guide to the MAOI Diet—Thinking Through Tyramine Troubles

This review article features comprehensive discussions on the dietary restrictions issued to patients taking a classic monoamine oxidase inhibitor (phenelzine, tranylcypromine, isocarboxazid), or high-dose (oral or transdermal) selegiline. It equips doctors with the knowledge to...
REVIEW ARTICLE

The Ham-D is not Hamilton’s Depression Scale

Introduction This article will demonstrate that the most widely used versions of the Hamilton Rating Scale for Depression (HAM-D) used in randomized clinical trials, the Guy 1976 HAM-D 1 and the SIGH-D, 2 have response...
COMPLICATED CASE HISTORY

Trichotieromania and Alopecia Areata Triggered by Aripiprazole- Methylphenidate Combo in an Autistic Child: The Nexus of Impulsivity-Compulsivity

Traditionally, compulsive disorders and impulsive disorders were regarded at opposite polarities—the former driven by harm-avoidance and the latter by reward-seeking. Convergent evidence from translational studies now suggests a shared tendency toward behavioural disinhibition, from failures...
LETTER TO THE EDITOR

Top-Up Clozapine for Risperidone LAI-Related Acute Dystonia and TR Bipolar in an Adolescent with ID-Putting the Cart before the Horse?

Objectives Young patients with intellectual disability (ID) have both diagnostic and therapeutic challenges. These include, inter alia, diagnostic overshadowing, diagnostic slippage and heightened vulnerability to adverse drug reactions. These would portent a generally poor prognostication....