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Psychopharmacology Bulletin › All Volumes & Issues › VOL 52 No. 1
PSYCHOPHARMACOLOGY BULLETIN

VOL 52 No. 1

Articles in This Issue

DRUG DISPOSITION AND PHARMACOKINETICS

Protein Biomarkers in Monocytes and CD4+ Lymphocytes for Predicting Lithium Treatment Response of Bipolar Disorder: a Feasibility Study with Tyramine-Based Signal- Amplified Flow Cytometry

Keming Gao*, Marzieh Ayati*, Mehmet Koyuturk, Joseph R. Calabrese, Stephen J. Ganocy, Nicholas M. Kaye, Hillard M. Lazarus, Eric Christian, David Kaplan
Purpose To determine if enhanced flow cytometry ( CellPrint™ ) can identify intracellular proteins of lithium responsiveness in monocytes and CD4 + lymphocytes from patients with bipolar disorder. Methods Eligible bipolar I or II patients...
Pages 8-35 Read Article
COMPLICATED CASE HISTORIES

Successful Add-on Viloxazine to Clozapine-Responsive Schizophrenia Mitigated Cognitive, Negative and Metabolic Domains

Ahmed Naguy, Reda Rushdy, Saxby Pridmore, Anubhuti Singh, Bibi Alamiri
Early-onset schizophrenia is notorious for poor prognostication and treatment-refractoriness. Clozapine remains a viable option, albeit off-label, but is clearly underutilized in this population. Use is typically fraught with panoply of drastic side effects. Here, authors...
Pages 57-60 Read Article
COMPLICATED CASE HISTORIES

Antipsychotic-Induced Laryngeal Dystonia

James Richard O’Neill, Clare Stephenson
We present the case of a young gentleman with diagnoses of bipolar affective disorder, high body mass index, and obstructive sleep apnoea. He was commenced on zuclopenthixol due to an inadequate response to quetiapine, but...
Pages 61-67 Read Article
REVIEW ARTICLE

Suvorexant in the Treatment of Difficulty Falling and Staying Asleep (Insomnia)

Amnon A Berger, Emily R Sottosanti, Ariel Winnick, Joseph Keefe, Elasaf Gilbert, Jamal Hasoon, Michael E Thase, Alan D Kaye, Omar Viswanath, Ivan Urits
Purpose of Review Insomnia affects more than 10% of the population and causes significant discomfort and disability. Suvorexant is an orexin receptor antagonist that specifically targets the wake-sleep cycle. This review summarizes recent and seminal...
Pages 68-90 Read Article
LETTER TO THE EDITOR

Low-Dose Risperidone for an Autistic Child with Comorbid ARFID and Misophonia

Ahmed Naguy, Abdul-Mohsen Al-Humoud, Saxby Pridmore, Mohamed Y Abuzeid, Anubhuti Singh, Dalal Elsori
Avoidant/Restrictive Food Intake Disorder and misophonia seem to be overrepresented in autism spectrum disorder. Literature is mute on psychopharmacotherapy in these complex presentations. Here, authors report on a challenging case of low-functioning ASD child with...
Pages 91-94 Read Article