VOL 51 No. 3

LETTER TO THE EDITOR

Can a ‘Shot’ Help Prevent Youth Re-Incarceration? Case Report on Use of a Long-Acting Injectable Antipsychotic in Incarcerated Youth

Arpit Aggarwal, Victoria Lindegaard

Incarcerated youth have a higher prevalence of mental disorders as compared to general population with rates of psychotic disorders about ten times more than the general adolescent population (Fazel, Doll et al. 2008). Serious mental...

Pages 8-9 Read Article

ORIGINAL RESEARCH

ADHD and Drug Holidays: Effects on Anthropometric Changes during Methylpenidate Treatment

Serkan Turan, Çağatay Ermiş, Victor Pereira-Sanchez, Mustafa Tunctürk, Aynur Akay Pekcanlar

Objectives: The current study evaluated the long-term effects of methylphenidate (MPH) discontinuation on growth parameters in Turkish children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Experimental design: 432 children and adolescents (aged 6–18 years) with ADHD...

Pages 10-26 Read Article

ORIGINAL RESEARCH

Long Acting Injectables and their Correlation with Subjectivity in Schizophrenia Spectrum Disorder

Ivano Caselli, Alessandra Gasparini, Marta Ielmini, Giulia Lucca, Stefano Amorosi, Nicola Poloni, Camilla Callegari

Nowadays, mental illness can no longer be considered as a mere list of symptoms corresponding to localized brain dysfunctions but rather as a disturbance of the patient’s subjectivity. Thus, a solid, qualitative study of patients’...

Pages 27-37 Read Article

ORIGINAL RESEARCH

The Role of Religiosity and Guilt in Symptomatology and Outcome of Obsessive Compulsive Disorder

Kumar Rakesh, Sharma Arvind, Bansal Pir Dutt, Bahetra Mamta, Saini Bhavneesh, Moria Kavita, Kaur Navneet, Gupta Shrutika, Bansal Priyanka, Kumar Arun, Kaur Harkamal, Kaur Jagdeep

Importance: Religiosity and guilt are commonly featured in obsessive-compulsive disorders (OCD). The role of religiosity and guilt in OCD has been frequently studied in the literature and suggested that greater religiosity/spirituality, paranormal beliefs, and magical...

Pages 38-49 Read Article

ORIGINAL RESEARCH

Treatment of Insomnia with Zaleplon in HIV+ Significantly Improves Sleep and Depression

Jennifer R. Goldschmied, Arjun Sengupta, Anup Sharma, Lynne Taylor, Knashawn H. Morales, Michael E. Thase, Michael E. Thase, Aalim Weljie, Matthew S. Kayser

More than 50% of individuals who are HIV positive report insomnia, which can reduce HIV treatment adherence, impair quality of life, and contribute to metabolic dysfunction. Major depressive disorder is also highly comorbid in this...

Pages 50-64 Read Article

COMPLICATED CASE HISTORY

Lithium-Induced Hyperparathyroidism: An Ill-defined Territory

Vishwanath Pattan, Balwinder Singh, Sahar S Abdelmoneim, Chaitra Gopinath, Vishnu Sundaresh

Lithium is the gold standard treatment for bipolar disorder. Studies have shown an association between lithium and hyperparathyroidism. However, there is limited data regarding the management of lithium-induced hyperparathyroidism. We present a clinical conundrum which...

Pages 65-71 Read Article

REVIEW ARTICLE

Struggling to find Effective Pharmacologic Options for Akathisia? B-CALM!

Srinagesh Mannekote Thippaiah, Rachel E. Fargason, Badari Birur

Akathisia is a movement disorder affecting the trunk and limbs, characterized by subjective and objective restlessness. Key signs include continual, repetitive rocking, leg shuffling, and fidgeting. Antipsychotic-induced akathisia is optimally managed by reducing the medication...

Pages 72-78 Read Article

REVIEW ARTICLE

Consistently Modest Antidepressant Effects in Clinical Trials: the Role of Regulatory Requirements

Arif Khan, Kaysee Fahl Mar, Walter A Brown

Despite being widely heralded following their discovery, the effectiveness and clinical utility of antidepressants has been questioned, in part due to the release of several decades of regulatory trial data. Upon investigation, contemporary regulatory trials...

Pages 79-108 Read Article

REVIEW ARTICLE

Developing an IV Ketamine Clinic for Treatment-Resistant Depression: a Primer

Sagar V. Parikh, Daniela Lopez, Jennifer L. Vande Voort, Jose Rico, Eric Achtyes, William Coryell, Andrew Goddard, Fernando Goes, John F. Greden, Balwinder Singh, Adam Kaplin, Mark A. Frye, Daniel Maixner, Brendon Watson, Karina Drake, Vijay Tarnal, Patricio Riva-Posse, William V. Bobo, None Bio-K Study Team

The efficacy of subanesthetic intravenous ketamine for treatment resistant depression (TRD) has spurred a growth of clinics nationwide that provide this service. Ketamine is an FDA-approved drug as an anesthetic but remains unapproved for psychiatric...

Pages 109-124 Read Article

REVIEW ARTICLE

MDMA to Treat PTSD in Adults

Dustin Latimer, Michael D. Stocker, Kia Sayers, Jackson Green, Adam M. Kaye, Alaa Abd-Elsayed, Elyse M. Cornett, Alan D. Kaye, Giustino Varrassi, Omar Viswanath, Ivan Urits

Post-traumatic stress disorder (PTSD) has become one of the most common psychiatric diagnosis in the United States specifically within the veteran population. The current treatment options for this debilitating diagnosis include trauma-focused psychotherapies along with...

Pages 125-149 Read Article