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Psychopharmacology Bulletin › All Volumes & Issues › VOL 42 No. 3
PSYCHOPHARMACOLOGY BULLETIN

VOL 42 No. 3

Articles in This Issue

ORIGINAL RESEARCH

Assessing Rates and Predictors of Tachyphylaxis During the Prevention of Recurrent Episodes of Depression With Venlafaxine ER for Two Years (PREVENT) Study

Anthony J. Rothschild, Boadie W. Dunlop, David L. Dunner, Edward S. Friedman, Alan Gelenberg, Peter Holland, James H. Kocsis, Susan G. Kornstein, Richard Shelton, Madhukar H. Trivedi, John M. Zajecka, Corey Goldstein, Michael E. Thase, Ron Pedersen, Martin B. Keller
Background: Antidepressant tachyphylaxis describes the return of apathetic depressive symptoms, such as fatigue and decreased motivation, despite continued use of a previously effective treatment. Methods: Data were collected from a multiphase, double-blind, placebo-controlled study that...
Pages 5-20 Read Article
DRUG DISPOSITION & PHARMACOKINETICS

Efficacy of Omega-3 Fatty Acids in – A Systematic Review and Metaanalysis

Nina V. Kraguljac, Victor M. Montori, Mani Pavuluri, High S. Chai, Brian S. Wilson, Sencan S. Unal
Objectives: Existing efficacy trials of Omega-3 (ω-3) fatty acids in mood disorders have yielded inconsistent results. The current paper is an effort to provide a systematic review and meta-analysis to evaluate efficacy of ω-3 fatty...
Pages 39-54 Read Article
COMPLICATED CASE HISTORIES

Neonatal Outcomes with the Use of Lamotrigine for Bipolar Disease in Pregnancy and Breastfeeding: A Case Series and Review of the Literature

Laura Wakil, C. Neill Epperson, Juan Gonzalez, John P. O’Reardon, Deborah R. Kim
The treatment of bipolar disorder in pregnant women and the postpartum period is a complex clinical issue requiring careful consideration of the risks involved in using psychotropic medications versus the benefits of successfully managing this...
Pages 91-98 Read Article
COMPLICATED CASE HISTORIES

Switching to Duloxetine Remits Ziprasidone – Associated Urinary Incontinence and Improves Neuropsychiatric Behavior in Dementia: Possible Relationship of Incontinence to 5HT2 Receptor Blockade

Edward C. Lauterbach, Florence T. Baralatei
Objectives: Urinary incontinence arising in dementia lowers patient quality of life, predicts caregiver burden and nursing home placement, and predisposes to adding additional medicines that can further impair cognition, behavior, and function. An understanding of...
Pages 99-105 Read Article