VOL 41 No. 2 Archives - MedWorks Media

LETTER TO THE EDITOR

Letter to the Editor: Glucose Testing in Patients Receiving Antipsychotic Pharmacotherapy

Dear Editor, We welcome the comments on our survey from Dr. Strouss and her colleagues. As they point out, our survey relied exclusively on physician self-reports, where the rate of reported plasma glucose testing was...

Pages 5-4 Read Article

LETTER TO THE EDITOR

Glucose Testing in Patients Receiving Antipsychotic Pharmacotherapy: Author Reply

Dear Editor, We welcome the comments on our survey from Dr. Strouss and her colleagues. As they point out, our survey relied exclusively on physician self-reports, where the rate of reported plasma glucose testing was...

Pages 7-8 Read Article

LETTER TO THE EDITOR

Letter to the Editor: Aggravation Of Schizophrenia by Clomipramine in a Patient With Comorbid Obsessive-compulsive Disorder

Dear Editor, Different reports suggest that more than 20% of patients with schizophrenia may have significant obsessive-compulsive symptoms.¹ The combination of an antiobsessional agent (SSRIs or clomipramine) and an antipsychotic has been recommended as an...

Pages 10-11 Read Article

ORIGINAL RESEARCH

Criteria for Defining Symptomatic and Sustained Remission in Bipolar I Disorder: a Post-Hoc Analysis of a 26-Week Aripiprazole Study (Study CN138-010)

Prakash S. Masand, MD, James Eudicone, MS, Andrei Pikalov, MD, PhD, Robert D. McQuade, PhD, Ronald N. Marcus, MD, Estelle Vester-Blokland, MD, and Berit X. Carlson, PhD

Objective: Remission is a key goal after treating an acute episode of bipolar I disorder, but greater understanding is needed of the correlation between attaining remission at a specific time point and maintaining sustained remission....

Pages 12-23 Read Article

ORIGINAL RESEARCH

Bipolar-I Depression Outpatient Treatment Quality and Costs in Usual Care Practice

Alisa B. Busch, MD, MS, Richard G. Frank, PhD, and Gary Sachs, MD

Objective: To examine the longitudinal usual care quality and costs of bipolar-I depression treatment in adults. Experimental Design: Observational study of claims data from a privately insured population, ages 18–64, diagnosed with bipolar-I depression (N...

Pages 24-39 Read Article

ORIGINAL RESEARCH

Addressing Methodological Issues in Studying Antidepressant Onset Efficacy Using Prespecified Sensitivity Analyses

Ilya Lipkovich, PhD, Craig H. Mallinckrodt, PhD, Apurva Prakash, BA, and Andrew A. Nierenberg, MD

Objectives: Assessing antidepressant onset efficacy presents substantial methodological challenges. Most assessments of onset efficacy are based on post hoc analyses. This article presents a case study of a prospectively designed trial to compare antidepressant onset...

Pages 29-39 Read Article

EVIDENCE-BASED MEDICINE

Are SNRIs More Effective than SSRIs? A Review of the Current State of the Controversy

Michael E. Thase, MD

The selective serotonin reuptake inhibitors (SSRI) are widely considered to be the first choice for antidepressant therapy. There is evidence from inpatient studies dating to 1986, however, suggesting that the tricyclic antidepressant clomipramine, which inhibits...

Pages 40-57 Read Article

COMPLICATED CASE HISTORY

Continuous Positive Airways Pressure Treatment in a Patient with Sleep Apnea—Hypopnea Syndrome and Coexisting Bipolar Disorder

Georgia Trakada, MD, Pashalis Steiropoulos, MD, and Demosthenes Bouros, MD, FCCP

We present a case of a 43-year-old woman with bipolar disorder who was diagnosed with sleep apnea–hypopnea syndrome (SAHS). After 10 days of treatment with continuous positive airways pressure (CPAP) during sleep, the patient presented...

Pages 89-92 Read Article

VOL 41 No. 2

Articles in This Issue

Letter to the Editor: Glucose Testing in Patients Receiving Antipsychotic Pharmacotherapy

Glucose Testing in Patients Receiving Antipsychotic Pharmacotherapy: Author Reply

Letter to the Editor: Aggravation Of Schizophrenia by Clomipramine in a Patient With Comorbid Obsessive-compulsive Disorder

Criteria for Defining Symptomatic and Sustained Remission in Bipolar I Disorder: a Post-Hoc Analysis of a 26-Week Aripiprazole Study (Study CN138-010)

Bipolar-I Depression Outpatient Treatment Quality and Costs in Usual Care Practice

Addressing Methodological Issues in Studying Antidepressant Onset Efficacy Using Prespecified Sensitivity Analyses

Are SNRIs More Effective than SSRIs? A Review of the Current State of the Controversy

Continuous Positive Airways Pressure Treatment in a Patient with Sleep Apnea—Hypopnea Syndrome and Coexisting Bipolar Disorder

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