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Psychopharmacology Bulletin › All Volumes & Issues › VOL 35 No. 2
PSYCHOPHARMACOLOGY BULLETIN

VOL 35 No. 2

Articles in This Issue

DRUG INTERACTIONS

Charleston Antidepressant Drug Interactions Surveillance Program (CADISP)

C. Lindsay DeVane, PharmD, John S. Markowitz, PharmD, Heidi L. Liston, PharmD, and S. Craig Risch, MD
A prospective antidepressant drug interaction surveillance program was established and collected data for over 4 years in Charleston, SC (Charleston Antidepressant Drug Interactions Surveillance Program, CADISP). One hundred and seventy patients were enrolled. The plasma...
Pages 50-61 Read Article
DRUG INTERACTIONS

A Pharmacokinetic Drug-Drug Interaction Study of Venlafaxine and Indinavir

Gary M. Levin, PharmD; Leigh Anne Nelson, PharmD; C. Lindsay DeVane, PharmD; Sandra L. Preston, PharmD; George Eisele, MD; and Stanley W. Carson, PharmD
Depression is a common occurrence in the human immunodeficiency virus (HIV)-infected population. Complications in treating depressed HIV-infected individuals include the use of multiple medications, additive side effects, and potentially significant drug–drug interactions. Based on the...
Pages 62-71 Read Article
COMPLICATED CASE HISTORIES

Treatment of Mania in Dementia With Electroconvulsive Therapy

William M. McDonald, MD, and Thomas R. Thompson, MD
Symptoms of mania have been given inadequate attention as a source of agitated behavior in the dementia patient. Characterized by elevation in mood or grandiosity, pressured speech, and impulsivity, mania is common among the elderly...
Pages 72-82 Read Article
GENERAL PSYCHOPHARMACOLOGY

Clinical Trials in Alzheimer’s Disease

Thomas E. Gillen, MD, MS; Keith M. Gregg, PhD; Huixing Yuan, PhD; Matthias C. Kurth, MD, PhD; and K. Ranga Krishnan, MB, ChB
The database of the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) is a seminal work in the field of cognitive dysfunction and Alzheimer’s disease. This 24-center study of 1,094 patients with Alzheimer’s disease...
Pages 83-96 Read Article
GENERAL PSYCHOPHARMACOLOGY

Management of Treatment-Refractory Panic Disorder

Sanjay J. Mathew, MD; Jeremy D. Coplan, MD; and Jack M. Gorman, MD
Treatment resistance remains a relatively common problem in panic disorder (PD) despite the success of the selective serotonin reuptake inhibitors (SSRIs) and cognitive behavioral therapy (CBT) as first-line agents. Factors contributing to medication treatment resistance...
Pages 97-110 Read Article
GENERAL PSYCHOPHARMACOLOGY

Merging the Cognitive Behavioral and Psychopharmacological Paradigms in Comparative Studies: Controversies, Issues, and Some Solutions

Jack M. Gorman, MD; David H. Barlow, PhD; Susan Ray; M. Katherine Shear, MD; and Scott Woods, MD
In the past, many studies attempting to compare pharmacological and psychosocial treatments for mood and anxiety disorders have been conducted by partisans of either approach. More recently, rigorously conducted, unbiased comparative studies have begun to...
Pages 111-124 Read Article