Skip to main content
RESEARCH ARCHIVE

Research Articles

Articles related to: mood stabilisers, mood stabilization, mood stabilizer, mood stabilizers

Research Articles

Showing articles tagged with:

mood stabilisers mood stabilization mood stabilizer mood stabilizers
COMPLICATED CASE HISTORY

Breaking the Cycle of Insomnia and Depression: Agomelatine in Adolescent Bipolar Disorder

Yiğit Özaydın, Enes Buğra Demir, Fevzi Tuna Ocakoğlu, Eyüp Sabri Ercan
Adolescent bipolar disorder (BD) is frequently accompanied by persistent sleep disturbances and depressive episodes that are resistant to standard treatments. Conventional antidepressants carry a risk of inducing mania or rapid cycling, particularly in younger patients....
Psychopharmacology Bulletin 56(3): 152-160, 2026/06/05
Pages 152-160 Read Article
GENERAL PSYCHIATRY

Maternal and Fetal Outcomes After Lamotrigine Use in Pregnancy: A Retrospective Analysis from an Urban Maternal Mental Health Centre in New Zealand

Chandni Prakash, Susan Hatters-Friedman, Charmian Moller-Olsen, Abigail North
Introduction Pregnancy is a vulnerable period for recurrence of bipolar disorder. Discontinuation of mood stabilisers during pregnancy and the postpartum period can significantly increase the risk of recurrence of bipolar disorder. Lamotrigine is an anti-epileptic...
Psychopharmacology Bulletin 46(2): 63-69, 2016/08/15
Pages 63-69 Read Article
ORIGINAL RESEARCH

Zonisamide for Bipolar Depression: A Randomized, Double Blind, Placebo-Controlled, Adjunctive Trial

Deborah Dauphinais, Michael Knable, Joshua Rosenthal, Mark Polanski, Norman Rosenthal
Objective This is the first multicenter, double blind, randomized, placebo-controlled trial to evaluate the safety and efficacy of adjunctive zonisamide for the treatment of bipolar depression. Experimental design One hundred two patients with bipolar disorder,...
Psychopharmacology Bulletin 44(2): 73-84, 2011/05/15
Pages 73-84 Read Article
ORIGINAL RESEARCH

Zonisamide for Bipolar Disorder, Mania or Mixed States: A Randomized, Double Blind, Placebo-Controlled Adjunctive Trial

Deborah Dauphinais, Michael Knable, Joshua Rosenthal, Mark Polanski, Norman Rosenthal
Objective This is the first multicenter, double blind, randomized, placebo-controlled trial to evaluate the safety and efficacy of adjunctive zonisamide for the treatment of bipolar mania or mixed state. Experimental design One hundred four patients...
Psychopharmacology Bulletin 44(1): 5-17, 2011/02/15
Pages 5-17 Read Article
ORIGINAL RESEARCH

Lamotrigine Adjunctive Therapy to Lithium and Divalproex in Depressed Patients with Rapid Cycling Bipolar Disorder and a Recent Substance Use Disorder: A 12-week, Double-Blind, Placebo-Controlled Pilot Study

Zuowei Wang, Keming Gao, David E. Kemp, Philip K. Chan, Mary Beth Serrano, Carla Conroy, Yiru Fang, Stephen J. Ganocy, Robert L. Findling, Joseph R. Calabrese
Objective: To pilot the efficacy and safety data of lamotrigine adjunctive therapy to lithium and divalproex in patients with rapid-cycling bipolar disorder (RCBD) and a recent substance use disorder (SUD). Method: Structured Clinical Interviews were...
Psychopharmacology Bulletin 43(4): 5-21, 2011/01/07
Pages 5-21 Read Article
ORIGINAL RESEARCH

Predictors of Non-Stabilization during the Combination Therapy of Lithium and Divalproex in Rapid Cycling Bipolar Disorder: A Post-hoc Analysis of Two Studies

Keming Gao, David E. Kemp, Zuowei Wang, Stephen J. Ganocy, Carla Conroy, Marry Beth Serrano, Martha Sajatovic, Robert L. Findling, Joseph R. Calabrese
To study predictors of non-stabilization (i.e., not bimodally stabilized for randomization or not randomized due to premature discontinuation) during open-label treatment with lithium and divalproex in patients with rapid-cycling bipolar disorder (RCBD) with or without...
Psychopharmacology Bulletin 41(1): 23-38, 2010/05/21
Pages 23-38 Read Article
GENERAL PSYCHOPHARMACOLOGY

Mood Stabilizers and Atypical Antipsychotics: Bimodal Treatments for Bipolar Disorder

Terence A. Ketter, MD, Henry A. Nasrallah, MD, and Andrea Fagiolini, MD
Treatment options for bipolar disorder have rapidly expanded over the last decade, but providing optimal management remains an elusive goal. The authors reviewed the literature on the efficacy of agents with the best clinical evidence...
Psychopharmacology Bulletin 39(1): 120-146, 2006/10/05
Pages 120-146 Read Article
TRANSLATIONAL NEUROSCIENCE

Modulators of the Glutamatergic System: Implications for the Development of Improved Therapeutics in Mood Disorders

Carlos A. Zarate, MD, Jorge Quiroz, MD, Jennifer Payne, MD, and Husseini K. Manji, MD
Mood disorders have traditionally been conceptualized as neurochemical disorders, but there is now evidence from a variety of sources demonstrating regional reductions in central nervous system volume as well as reductions in the numbers and/or...
Psychopharmacology Bulletin 36(4): 35-83, 2002/10/15
Pages 35-83 Read Article
DRUG INTERACTIONS

Pharmacokinetics of Mood Stabilizers and New Anticonvulsants

Po W. Wang, MD, and Terence A. Ketter, MD
Mechanisms of action, efficacy spectra, pharmacokinetics, and adverse effects differentiate the mood stabilizers lithium, carbamazepine (CBZ), and valproate (VPA). Lithium, which has a low therapeutic index, is excreted through the kidneys, resulting in renally mediated,...
Psychopharmacology Bulletin 36(1): 44-66, 2002/01/15
Pages 44-66 Read Article
TRANSLATIONAL NEUROSCIENCE

Bioelectrical Modulators and the Cell Membrane in Psychiatric Medicine

Ralph Ryback, MD
The term bioelectrical modulators specifically applies to anticonvulsant drugs and mood stabilizers; however, it also embodies the larger more generic concept that bioelectrical modulators can mitigate any pathological condition caused by a dysregulation of the...
Psychopharmacology Bulletin 35(4): 5-44, 2001/10/15
Pages 5-44 Read Article