Abstract
Valproic acid has clear efficacy in the treatment of partial epilepsies. Its multiple mechanisms predicted its broad spectrum of efficacy and preclinical experimental data prompted its clinical use. Valproic acid’s efficacy has been repeatedly demonstrated in clinical trials over the past 25 years. Its efficacy in the treatment of partial epilepsies is similar or better than both the traditional and new antiepileptic drugs. Its side effect profile is well known and manageable, especially with extended-release formulations.
Keywords
adverse effects, divalproex, divalproex-for-partial-epilepsies, divalproex-sodium, efficacy, mechanism-of-action, michael-c-smith, partial-epilepsies, partial-seizures, valproate, valproic acid
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How to Cite
Michael C. Smith, MD. The Efficacy of Divalproex for Partial Epilepsies.
Psychopharmacology Bulletin.
2003/07/15; 37(Suppl. 2):54-66.
https://doi.org/10.64719/pb.7075
