Alzheimer’s disease, dementia, and neurocognitive disorders — diagnostics, disease-modifying therapies, and cognitive research.
Bristol Myers Squibb announced that the US Food and Drug Administration (FDA) has granted Fast Track Designation to BMS-986446, a potential best-in-class anti–microtubule binding region tau (anti–MTBR-tau) antibody…
Semaglutide, a medication for type 2 diabetes (T2D), is associated with a 20%-46% reduced risk for Alzheimer’s disease-related dementia compared with other antidiabetic drugs. A study analyzed electronic…
A novel blood test that detects a key biomarker for Alzheimer’s disease (AD) could help physicians more accurately determine the presence and track disease progression. The test measures…
The US Food and Drug Administration (FDA) has approved the anti-amyloid beta protofibril antibody lecanemab (Leqembi, Eisai) for the treatment of early Alzheimer’s disease (AD). The agency approved…
According to well-placed recent reports, Biogen Inc withdrew its paper that analyzed results from the clinical trials of its controversial Alzheimer’s drug, Aduhelm, that was submitted to medical…
Three members of a US Food and Drug Administration (FDA) advisory committee are explaining why they do not support approval of the drug aducanumab (Biogen, Eisai) for the…
Daily intranasal insulin may be effective in slowing progression of mild cognitive impairment (MCI) or Alzheimer’s disease (AD), new research suggests. The findings were presented at the Alzheimer’s…
Adding the Alzheimer drug memantine (Namenda, Allergan) to treatment with a selective serotonin reuptake inhibitor may improve depressive symptoms, executive function, and other outcomes in older patients with…
Treatment with the investigational compound elenbecestat reduced brain amyloid beta levels and was safe and well-tolerated, according to Phase 2 clinical trial results. The presence of amyloid beta plaques is…
Alzheimer’s disease startup Cortexyme was able to round up $76 million in funding for a potentially first-in-class treatment, while other companies are looking to move away from the…
Longer Lives, Better Living By Bill Gates In every part of the world, people are living longer than they used to. Thanks to scientific advancements, fewer people die…
Viewpoint November 6, 2017 Advance Directives for Dementia: Meeting a Unique Challenge By Barak Gaster, Eric B. Larson, and J. Randall Curtis In the coming years, an increasing number of people will experience…
Is dorsolateral prefrontal cortex plasticity impaired in Alzheimer disease? Yes, according to researchers writing in JAMA Psychiatry. Dorsolateral prefrontal cortex plasticity is impaired in Alzheimer disease and is associated…
Richard J. Kryscio, Erin L. Abner, Allison Caban-Holt, et al. Key Points Question Can vitamin E or selenium prevent dementia in asymptomatic older men? Findings The Prevention of…
In a recent study, researchers looked at the possibility of using nutritional intervention to slow the onset of certain Alzheimer’s symptoms. The study involved a particular nutritional drink…
