25 08, 2017

Association of Lithium in Drinking Water With the Incidence of Dementia

By | 2017-08-25T15:08:33+00:00 August 25th, 2017|Brainscience Blogs|0 Comments

Original Investigation Association of Lithium in Drinking Water With the Incidence of Dementia Lars Vedel Kessing,  Thomas Alexander Gerds,  Nikoline Nygård Knudsen, Lisbeth Flindt Jørgensen, Søren Munch Kristiansen, Denitza Voutchkova, Vibeke Ernstsen, Jörg Schullehner, Birgitte Hansen, Per Kragh Andersen, Annette Kjær Ersbøll Question  Is a higher lithium level in drinking water associated with a decreased incidence of dementia? Findings  In this Danish nationwide, population-based, [...]

9 08, 2017

Psychopharmacology Bulletin, V47, N3: Links to In-Depth Articles

By | 2017-10-10T16:16:48+00:00 August 9th, 2017|Brainscience Blogs|0 Comments

Psychopharmacology Bulletin, V47, N3: Links to In-Depth Articles   ORIGINAL PRESENTATIONS   Baseline Demographics and Characteristics From a Paliperidone Palmitate Study in Subjects with Recent-Onset Schizophrenia or Schizophreniform Disorder. By Brianne Brown, Larry Alphs, Ibrahim Turkoz, Yong Yue   Correlation of Caregiver Burden and Baseline Characteristics of Caregivers and Patients [...]

20 06, 2017

FDA Clears New Methylphenidate Formulation for ADHD

By | 2017-06-20T18:08:41+00:00 June 20th, 2017|Brainscience Blogs|0 Comments

The US Food and Drug Administration (FDA) has approved a new formulation of methylphenidate for children with attention-deficit/hyperactivity disorder (ADHD). Cotempla XR-ODT (Neos Therapeutics Inc) is the first and only methylphenidate extended-release orally disintegrating tablet for the treatment of ADHD in patients aged 6 to 17 years, the company said [...]

19 06, 2017

Teen Depression Linked to Persistent Sleep-Disordered Breathing

By | 2017-06-19T22:55:41+00:00 June 19th, 2017|Brainscience Blogs|0 Comments

By Megan Brooks BOSTON — Sleep-disordered breathing (SDB) may play a role in persistent depressive symptoms and poor response to standard pharmacologic treatments in adolescents, new research suggests. Screening adolescents with treatment-resistant depression (TRD) for SBD "may be clinically valuable, since SDB is readily treatable," said Teena Chase, MD, PhD, Department [...]

19 06, 2017

Lithium: New Uses for Old Psychotropic

By | 2017-06-19T22:45:52+00:00 June 19th, 2017|Brainscience Blogs|0 Comments

By Nassir Ghaem Wide-Ranging Benefits At the recent American Psychiatric Association annual meeting in San Diego, an update symposium was presented on the topic of "Lithium: Key Issues for Practice."[1] In a session chaired by Dr David Osser, associate professor of psychiatry at Harvard Medical School, presenters reviewed various aspects of [...]

19 06, 2017

Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia

By | 2017-06-19T22:30:20+00:00 June 19th, 2017|Brainscience Blogs|0 Comments

Original Investigation By Jari Tiihonen, MD,  Ellenor Mittendorfer-Rutz, Maila Majak; et al   Key Points Question  Are there any clinically meaningful differences between specific antipsychotic medications or routes of administration regarding the risk of psychiatric rehospitalization or other treatment failure? Findings  This database study of a nationwide cohort of patients using within-individual analysis to eliminate [...]

14 06, 2017

Experimental ADHD Drugs Aimed at Aggression, Genetic Targets

By | 2017-06-14T12:51:37+00:00 June 14th, 2017|Brainscience Blogs|0 Comments

MIAMI – Medications in development for the treatment of attention-deficit/hyperactivity disorder (ADHD) target specific behaviors, such as impulsive aggression, and genes that involve the glutamatergic network, new research shows. In the first of two studies presented here at the American Society of Clinical Pharmacology (ASCP), researchers reported on improvements in [...]

8 06, 2017

Quetiapine extended release versus aripiprazole in children and adolescents with first-episode psychosis: the multicentre, double-blind, randomised tolerability and efficacy of antipsychotics (TEA) trial

By | 2017-06-08T10:47:39+00:00 June 8th, 2017|Brainscience Blogs|0 Comments

Anne Katrine Pagsberg , Pia Jeppesen, Dea Gowers Klauber, Karsten Gjessing Jensen, Ditte Rudå, Marie Stentebjerg-Olesen, Peter Jantzen, Simone Rasmussen, Eva Ann-Sofie Saldeen, Britt Glenn Lauritsen, Niels Bilenberg, Anne Dorte Stenstrøm, Louise Nyvang , Sarah Madsen, Thomas M Werge, Theis Lange ,Christian Gluud, Maria Skoog, Peter Winkel, Jens Richardt, M Jepsen, Birgitte Fagerlund, Christoph U Correll, Anders Fink-Jensen Summary Background Head-to-head trials to guide antipsychotic treatment choices for paediatric psychosis are urgently needed because [...]